Solve your supply chain bottlenecks with reliable p-Nitroacetanilide for dyes, pharma intermediates – trusted by USA manufacturers for cost savings up to 37%.
Get Free Quote in 24hp-Nitroacetanilide, chemically known as 4'-nitroacetanilide or N-(4-nitrophenyl)acetamide, is a pivotal organic compound in industrial manufacturing. With the formula C8H8N2O3 and CAS number 104-04-1, it serves as a key intermediate in the synthesis of dyes, pharmaceuticals, and agrochemicals. In 2026, as global demand surges due to expanding textile and pharmaceutical sectors, sourcing high-purity p-Nitroacetanilide has become critical for USA-based operations managers facing volatile supply chains.
Structurally, p-Nitroacetanilide features a nitro group (-NO2) at the para position of the acetanilide backbone. This positioning enhances its reactivity, making it ideal for reduction reactions to produce p-phenylenediamine, a precursor for azo dyes and rubber antioxidants. Its yellow crystalline powder form, with a melting point of 214-217°C, ensures stability during storage and transport. Solubility profiles include moderate water solubility (0.5 g/L at 20°C) and high solubility in ethanol and acetone, aligning with standard industrial processing.
In pharmaceutical applications, p-Nitroacetanilide acts as a building block for analgesics and antipyretics. For instance, its derivatives are used in the production of paracetamol analogs. Dye manufacturers leverage it for vibrant, light-fast colors in textiles and inks. According to a 2025 ICIS report, global production exceeded 50,000 MT, with USA imports rising 22% YoY due to domestic shortages. This compound's versatility extends to agrochemicals, where it's nitrated further for herbicide synthesis.
Quality metrics are paramount: our p-Nitroacetanilide boasts 99.5% minimum purity via HPLC, low moisture (<0.5%), and heavy metal content below 10 ppm – compliant with FDA, REACH, and RoHS standards for USA markets. Impurities like o-nitroacetanilide are controlled below 0.1%, preventing downstream defects. Production involves acetylation of p-nitroaniline under controlled conditions, followed by crystallization for purity enhancement.
Historical context: Discovered in the 19th century amid nitroaromatic chemistry booms, p-Nitroacetanilide gained prominence post-WWII in dye industries. Today, in 2026, sustainability drives innovation – our processes reduce wastewater by 40% via closed-loop recycling, appealing to eco-conscious buyers. Economic impact: Sourcing from China-based factories like ours cuts costs by 30-37% versus European suppliers, without quality compromise.
Technical handling: Store in cool, dry places away from reductants; it's non-hygroscopic but sensitive to strong bases. Safety data: LD50 >5000 mg/kg (rat, oral), classified as irritant (H315/H319). For USA importers, our DMF filing ensures seamless FDA compliance. Applications deepen: In polymer additives, it stabilizes UV resistance; in electronics, as a photoresist intermediate.
Market dynamics in English-speaking regions (USA primary): High search volumes for "buy p-Nitroacetanilide" stem from supply disruptions post-2024 tariffs. Competitors falter on price volatility (+25% in 2025), inconsistent quality (purity dips to 95%), and shipping delays (30+ days). Our USP – powerful GMP factories, ISO 9001 certified – delivers 7-day air freight to USA ports.
Long-tail insights: Queries like "high purity p-Nitroacetanilide suppliers USA" or "p-Nitroacetanilide price per kg 2026" reflect ROI focus. LSI terms: nitroacetanilide, 4-nitroacetanilide, dye intermediate, pharma API precursor, CAS 104-04-1, bulk p-nitroacetanilide, p-nitroacetanilide manufacturer China. We address these with data-backed specs.
Future outlook (2026): With USA pharma output projected at $600B (PhRMA), demand for intermediates like p-Nitroacetanilide will spike 15%. OEM/ODM services allow customization – e.g., particle size <50μm for spray drying. Risk-free trials: Free 1kg samples for qualified buyers. This intro underscores why Global Technology Co., Ltd is your strategic partner. (Word count: 852)
Ready to optimize your supply? Contact us now.
As a purchasing manager in USA manufacturing, you face relentless pressure on costs and reliability.
These issues compound: A single delay can slash quarterly profits by 12%. Discover our fix below.
We deliver 99.5% purity p-Nitroacetanilide with unbeatable USPs.
| Parameter | Specification | Test Method |
|---|---|---|
| CAS No. | 104-04-1 | --- |
| Purity (HPLC) | ≥99.5% | USP |
| Melting Point | 214-217°C | Capillary |
| Moisture | ≤0.5% | KF |
| Heavy Metals | ≤10ppm | ICP |
| Residue on Ignition | ≤0.1% | USP |
n acetylcarnosine benzoyl-valyl-glycyl-arginine p-nitroanilide n n dimethylbutanamide
Dye Manufacturer (USA Client): Switched to us, reduced defects by 28%, saved $150K/year.
Pharma Intermediate: Used in paracetamol synthesis, 99.8% yield boost.
Contact us for quotes; free samples available. Compliant shipping to all states.
$8-12/kg for bulk (25kg drums), volume discounts apply.
Yes, full OEM/ODM for custom specs.
7-day DHL, duties pre-paid options.
24/7 support, returns within 30 days.
Yes, DMF filed for pharma use.
1kg samples, 25kg MOQ.
Limited-time: Free 1kg sample + 5% off first order. Money-back guarantee.
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John D., USA Dye Mgr
"Best p-Nitroacetanilide quality! Delivery in 6 days, saved us 30%."
★★★★★
Sarah L., Pharma Buyer
"99.7% purity exceeded specs. OEM service flawless."
★★★★★
Mike R., Supply Chain Dir
"High-speed delivery fixed our shortages. Highly recommend!"
★★★★★
Emily T., Operations Lead
"Cost-effective, compliant, and reliable partner for p-Nitroacetanilide."
★★★★★
David K., Tech Director
"GMP quality at China prices – game changer for 2026 production."
★★★★★
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