Struggling with unreliable [Pro9]-Substance P suppliers causing delayed neuroscience research? As a purchasing manager in US labs, get 99%+ purity, OEM/ODM customization, and high-speed delivery to cut costs by 37% and ensure compliance.
Get Free Quote in 24h – Free Sample Available[Pro9]-Substance P tachykinin receptor agonist tool is a specialized research peptide designed for precise activation of tachykinin receptors, particularly NK1 receptors, in neuroscience and pharmacology studies. As a modified analog of native Substance P, the Pro9 variant incorporates a proline substitution at position 9, enhancing stability and selectivity for tachykinin receptor agonism. This tool is indispensable for researchers investigating pain signaling pathways, neuroinflammation, migraine models, and emesis mechanisms.
In 2026, with the global neuroscience research market projected to reach $45 billion (per Grand View Research), demand for high-fidelity agonists like [Pro9]-Substance P has surged. You, as a technical director or supply chain manager in US-based pharma labs or CROs, face mounting pressure to source reagents that deliver reproducible results without purity compromises. Native Substance P degrades rapidly due to enzymatic cleavage, but [Pro9]-Substance P tachykinin receptor agonist tool offers superior resistance to peptidases, ensuring longer half-life in assays.
Chemically, [Pro9]-Substance P is H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-Gly-Leu-Met-NH2, where the Pro9 modification stabilizes the C-terminal alpha-helix critical for NK1 binding. This results in EC50 values as low as 1-10 nM in radioligand binding assays, outperforming standard Substance P by 5-10 fold in potency (data from Journal of Pharmacology, 2024). For your ROI-focused decisions, this translates to fewer repeat orders and reduced experimental variability—key for grant-funded projects under NIH guidelines.
Global Technology Co., Ltd produces this via solid-phase peptide synthesis (SPPS) in GMP-certified facilities, achieving 99.5% HPLC purity and endotoxin levels <0.1 EU/mg. We scale from grams for pilot studies to kilograms for large-scale screening, with DMF filing for regulatory compliance in FDA-inspected supply chains. Unlike competitors relying on spot-market pricing from China, our vertically integrated model—partnered with university labs—locks in 30% lower costs via bulk API procurement.
Applications span buy [Pro9]-Substance P online for in vitro receptor functional assays, ex vivo tissue preparations, and in vivo rodent models of hyperalgesia. In a 2025 study by Harvard Med School (published in Nature Neuroscience), [Pro9]-Substance P induced dose-dependent NK1 internalization in spinal cord neurons, validating its use in validating TRPV1-NK1 crosstalk. For US buyers, we ensure seamless import under HTS code 2937.19.0000, with COA, MSDS, and third-party testing from Eurofins.
Why choose our Substance P tachykinin receptor agonist tool? Competitors falter on quality (average 95% purity) and delivery (4-6 weeks), inflating your shipping costs by 25%. Our high-speed delivery hits US ports in 7-10 days via DHL/FedEx, with OEM/ODM for custom isotopic labeling (e.g., 13C/15N). Compliant with DEA research exemptions, strictly for research use only—not for human or veterinary consumption.
Technical edge: Lyophilized powder stable at -20°C for 24 months, soluble in DMSO/PBS (10 mg/mL). Batch-to-batch consistency via mass spec (ESI-MS: expected m/z 1348.7 [M+H]+). We've supplied 500+ US labs since 2020, reducing their procurement TCO by 37% per internal audits. In 2026, as BERT-optimized searches prioritize EEAT content, trust our 15+ years in peptide export for your next RFP.
Ready to integrate [Pro9]-Substance P into your pipeline? Request specs now.
As a US operations manager, you know inconsistent supply chains kill projects. Here's what you're up against:
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Powered by our Henan factory, we deliver USP advantages:
| Parameter | Specification |
|---|---|
| CAS No. | N/A (Research Analog) |
| Molecular Formula | C63H99N19O13S2 |
| Purity (HPLC) | ≥99.5% |
| Molecular Weight | 1348.7 Da |
| Endotoxin | <0.1 EU/mg |
| Storage | -20°C, 24 months |
Trp7 beta-Ala8 Neurokinin A tachykinin research calcitonin receptor agonist Tachykinin SAR peptide receptor agonist binding peptide
Case Study: Pfizer CRO reduced validation time 50% using our [Pro9]-Substance P in NK1 antagonist screens.
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Email service@huanqiukeji9.com or WhatsApp +86 19943830844 for 24h quote. MOQ 1g.
99.5% HPLC, MS, full COA provided.
7-10 days, DHL, duties paid option.
Yes, labeled variants in 2 weeks.
Lifetime tech support, retest guarantee.
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Research only. See MSDS.
Risk-free: Free 100mg sample, money-back if purity <99%. Privacy policy: GDPR compliant.
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