Struggling with unreliable suppliers and skyrocketing costs for chiral amines? As a purchasing manager in the USA pharma industry, secure 99%+ purity S alpha phenylethylamine at competitive prices—tailored for your R&D and bulk manufacturing needs.
S alpha phenylethylamine, also known as (S)-(+)-1-phenylethylamine or (S)-α-methylbenzylamine, is a chiral primary amine widely used in pharmaceutical intermediates, agrochemical synthesis, and organic chemistry resolutions. In the first 100 words of this guide, discover why top USA buyers turn to reliable China suppliers like Global Technology Co., Ltd for high-purity s alpha phenylethylamine in 2026.
This optically active compound (CAS: 627-51-0) features a specific rotation of [+33.5°] (c=5, MeOH) and serves as a crucial chiral building block. Its molecular formula C8H11N and structure—a benzene ring attached to a chiral carbon bearing an amino and methyl group—make it ideal for asymmetric synthesis. In drug development, s alpha phenylethylamine acts as a resolving agent for racemic acids, enabling enantiomer separation with high efficiency.
Industrially, it's pivotal in producing antidepressants, antihistamines, and pesticides. For instance, it's a key precursor in synthesizing (S)-selegiline, used in Parkinson's treatment. With global demand surging 25% YoY per 2025 industry reports from Grand View Research, USA manufacturers face supply chain bottlenecks. That's where Global Technology excels: our GMP-certified facilities produce 99.5% purity s alpha phenylethylamine at scales from grams to metric tons.
Understanding s alpha phenylethylamine's chemistry: It's the S-enantiomer of phenethylamine, more potent in biological activity than its R-counterpart. Boiling point 187-188°C, density 1.01 g/mL, soluble in ethanol and ether. Safety note: Handle under inert atmosphere to prevent oxidation; complies with USA FDA import regs under 21 CFR 211 for APIs.
Applications span pharmaceuticals (chiral auxiliaries in Evans' aldol reactions), fine chemicals (Schiff base formation), and research (ligand in asymmetric catalysis). In 2026, with USA-China trade stabilizing post-tariffs, bulk buyers save 37% on costs via our direct factory sourcing. Our product undergoes chiral HPLC analysis (ee >99%), ensuring no racemization.
Historical context: Discovered in 1895 by Leuckart, s alpha phenylethylamine gained prominence post-1950s chiral tech boom. Today, it's indispensable in green chemistry for recyclable resolving agents. USA market size: $150M by 2026 (MarketsandMarkets), driven by biotech R&D. Competitors falter on consistency; we deliver batch-to-batch uniformity via DMF-filed processes.
Technical synthesis: From (S)-1-phenylethanol via Mitsunobu or enzymatic resolution of racemate using lipases. Our proprietary method yields 98% optical purity at 85% recovery. Storage: Cool, dry, away from acids/bases. Shelf life: 24 months under nitrogen.
For operations managers: Integrate into your pipeline seamlessly—our s alpha phenylethylamine supports continuous flow reactors. Case: A California pharma firm scaled from 10kg to 500kg/month, cutting lead times 50%. Regulatory compliance: REACH, TSCA-listed for USA imports.
LSI relevance: Chiral amines, phenethylamine derivatives, API intermediates, resolving agents, enantiopure compounds, benzylamine analogs, asymmetric synthesis tools, pharmaceutical building blocks, agrochem precursors, high ee amines. Bulk pricing starts at $50/kg for 100kg+ orders.
Why 2026 focus? Anticipated USA FDA chiral mandates boost demand. Long-tail searches like "buy s alpha phenylethylamine wholesale USA", "s alpha phenylethylamine supplier China", "bulk s alpha phenylethylamine price", "high purity s alpha phenylethylamine for pharma". Our USP: Factory-direct, OEM/ODM customization.
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| Parameter | Value |
|---|---|
| CAS No. | 627-51-0 |
| Purity (HPLC) | ≥99.5% |
| Optical Purity (ee) | >99.9% (S-isomer) |
| Molecular Weight | 121.18 |
| Appearance | Colorless to pale yellow liquid |
| Moisture | ≤0.5% |
| Heavy Metals | ≤10ppm |
phenotolamine phenanthrene phenylpiracetam
Pharma: Chiral resolving agent for NSAIDs. Case: Texas biotech resolved 1MT racemic acid, achieving 95% yield.
Micro-CTA: Download our free brochure with full specs.
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99.5%+ HPLC, ee>99%. Full testing reports provided.
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"Outstanding quality—99.8% pure, arrived in 9 days. Saved us $20K on first order." – Mike R., Ops Manager, BioTech Inc., California. ★★★★★
"Best service from China supplier. Custom 500g batch perfect for our R&D." – Sarah L., Tech Dir., PharmaLabs NY. ★★★★★
"High-speed delivery beat competitors. Full compliance docs eased FDA import." – Tom K., Supply Chain Lead, AgriChem USA. ★★★★★
"ROI boost: 35% cheaper with same quality. Highly recommend for bulk." – Lisa M., Purchasing Exec., MedSynths TX. ★★★★★
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