LHRH-Ⅲ, lamprey CAS NO.147859-97-0
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | LHRH-Ⅲ, lamprey |
| CAS NO. | 147859-97-0 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C59H75N18O14 |
| Molecular Weight | 1259.4 g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water, dilute acetic acid, DMSO |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Lamprey gonadotropin-releasing hormone III; involved in regulating reproductive axis function, and can be used in comparative endocrinology, reproductive physiology, and evolutionary research. |
| Storage Conditions | Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
LHRH-Ⅲ, lamprey functions as a neuroendocrine peptide that binds to specific G-protein coupled gonadotropin-releasing hormone receptors in the lamprey pituitary. This binding activates phospholipase C-mediated signaling pathways, leading to increased intracellular calcium levels and protein kinase C activation. The downstream effects stimulate the synthesis and release of gonadotropins, which regulate gonadal development, steroidogenesis, and reproductive behaviors. The peptide exhibits distinct receptor-binding properties compared to mammalian GnRH isoforms, providing insights into the evolutionary adaptation of neuroendocrine systems. Its structural features, including conserved N-terminal pyroglutamate and C-terminal amidation, contribute to receptor recognition and metabolic stability in aquatic environments.
2.PRODUCT INDICATIONS
3.CLINICAL EFFICACY OF PRODUCT
4.DELIVERY & SHIPPING
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