Loureirin D CAS NO.119425-91-1

Loureirin D CAS NO.119425-91-1

Loureirin D CAS NO.119425-91-1

Loureirin D CAS NO.119425-91-1

Loureirin D CAS NO.119425-91-1

Loureirin D, also known as Dragon's Blood D, is a high-purity natural dihydrochalcone compound isolated from the resin of Dracaena cochinchinensis(Dragon's Blood), primarily supplied as a research-grade reagent or pharmaceutical intermediate for scientific laboratories. It features distinct physicochemical properties including specific solubility in organic solvents and stability under standard conditions, making it an ideal candidate for pharmacological screening, mechanism exploration, and as a reference standard in analytical chemistry. This product is tailored for researchers focusing on natural product drug discovery, offering a reliable molecular template to investigate novel therapeutic agents against complex diseases.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Loureirin D
CAS NO.
119425-91-1
Appearance
White to off-white crystalline powder
Molecular Formula
C16H16O5
Molecular Weight
288.30 g/mol
Purity (RP-HPLC)
≥98.0%
Solubility

Soluble in methanol, DMSO; sparingly soluble in water

Endotoxin
≤10 EU/mg
Biological Activity
Antithrombotic (P2Y12 antagonism), anti-inflammatory, potential for platelet aggregation inhibition
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Loureirin D exerts its primary biological effects by acting as a selective antagonist of the P2Y12 receptor, where it binds to the ADP-responsive purinergic receptor on platelet membranes to block the initiation of thrombotic signaling cascades and prevent platelet activation, aggregation, and adhesion. Additionally, it modulates key inflammatory and fibrotic pathways by suppressing the NF-κB signaling to inhibit pro-inflammatory cytokine production (such as TNF-α, IL-1β, and IL-6) and down-regulating the TGF-β1/Smad pathway to reduce fibroblast activation and extracellular matrix deposition. These multi-target interactions allow the compound to interfere with critical disease processes at the cellular signaling level, providing a foundation for its diverse pharmacological profile.

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2.PRODUCT INDICATIONS

This product is indicated for use in preclinical and in vitro research settings targeting thrombotic disorders, inflammatory diseases, fibrotic conditions, and certain proliferative pathologies such as specific cancer cell models. It is suitable for scientists and pharmaceutical developers studying antithrombotic agents, neuroprotective drugs (given its observed blood-brain barrier protective effects), anti-fibrotic therapies for organs like the liver and lungs, and wound-healing biomaterials due to its traditional medicinal background. Researchers utilizing Loureirin D are typically engaged in drug discovery pipelines, pharmacological mechanism validation, or the development of standardized analytical methods for natural product quality control.

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3.CLINICAL EFFICACY OF PRODUCT

While direct clinical application in humans is currently not established as the product is strictly for research use, preclinical studies demonstrate significant efficacy in animal models, such as notably ameliorating renal dysfunction and tissue damage in renal ischemia-reperfusion models and reducing cerebral infarct size in stroke models by inhibiting neuronal ferroptosis. Research indicates it effectively improves cognitive impairment in Alzheimer’s disease models via ERα pathways and promotes cell survival in Parkinson’s disease cellular models by suppressing apoptosis and oxidative injury. These consistent experimental outcomes highlight its strong therapeutic potential and biological reliability in controlled research settings, guiding future drug development pipelines despite the absence of current human trial data.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags: Loureirin D, Dragon's Blood D, Dihydrochalcone, P2Y12 Receptor Antagonist, Antiplatelet Agent, Natural Product, Pharmaceutical Intermediate, Research Chemical, Antithrombotic, Anti-inflammatory, Anti-fibrotic, NF-κB Inhibitor, Dracaena cochinchinensis Extract, Standard Reference Material, Biomedical Research.


If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157

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