Mono(6-amino-6-deoxy)-β-cyclodextrin CAS NO.29390-67-8

Mono(6-amino-6-deoxy)-β-cyclodextrin CAS NO.29390-67-8

Mono(6-amino-6-deoxy)-β-cyclodextrin CAS NO.29390-67-8

Mono(6-amino-6-deoxy)-β-cyclodextrin CAS NO.29390-67-8

Mono(6-amino-6-deoxy)-β-cyclodextrin CAS NO.29390-67-8

Mono(6-amino-6-deoxy)-β-cyclodextrin is a chemically modified β-cyclodextrin derivative characterized by the substitution of a primary hydroxyl group at the 6-position with a highly reactive amino group, resulting in a unique functional molecule that combines the classic hydrophobic cavity inclusion capability with enhanced chemical reactivity. This white to off-white amorphous powder is hygroscopic and readily soluble in water, DMSO, and DMF, making it a versatile building block for advanced supramolecular chemistry and pharmaceutical research. Its distinct structural feature allows it to serve not only as a superior host molecule for encapsulating poorly water-soluble drugs but also as a key intermediate for further chemical conjugation, bridging the gap between traditional cyclodextrin applications and modern targeted delivery systems.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Mono(6-amino-6-deoxy)-β-cyclodextrin
CAS NO.
29390-67-8
Appearance
White to off-white crystalline powder
Molecular Formula
C42H71NO34
Molecular Weight
1134.00 g/mol
Purity (RP-HPLC)
≥98.0%
Solubility

Freely soluble in water, DMSO, DMF; slightly soluble in methanol

Endotoxin
≤10 EU/mg
Biological Activity
Effective complexation with hydrophobic molecules; enhances solubility of poorly water-soluble drugs
Storage Conditions
Store at 2–8°C, protected from light and moisture
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The primary mechanism of action revolves around the dual functionality of the molecule: the hydrophobic inner cavity provides a microenvironment to accommodate guest molecules through non-covalent interactions, while the exposed amino group at the rim offers a site for protonation in neutral to acidic pH conditions, facilitating electrostatic interactions with anionic compounds. Additionally, this primary amine acts as a robust chemical handle that enables covalent linkage to carboxylic acids, active esters, aldehydes, and other electrophiles under mild conditions, allowing for the rational design of complex architectures such as polymer conjugates, surface-immobilized sensors, and targeted nanocarriers. This combination of host-guest complexation and straightforward derivatization makes it a dynamic tool for modulating the physicochemical properties of bioactive agents and constructing responsive delivery vehicles

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2.PRODUCT INDICATIONS

This product is indicated primarily for research and development purposes within pharmaceutical, biochemical, and material science sectors, targeting scientists and formulators working on drug solubilization, stabilization, and novel delivery platforms. It is particularly suited for professionals developing inclusion complexes to enhance the bioavailability of hydrophobic drugs, as well as researchers designing functionalized cyclodextrins for use in catalysis, chiral separation, and the fabrication of biosensors or diagnostic probes. Furthermore, it serves as a critical reagent for synthetic chemists aiming to introduce cyclodextrin moieties into larger molecular frameworks or surfaces, thereby catering to the needs of advanced material engineers and bioconjugation specialists.

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3.CLINICAL EFFICACY OF PRODUCT

As a chemical reagent and research intermediate, Mono(6-amino-6-deoxy)-β-cyclodextrin does not possess direct clinical efficacy in the therapeutic sense; rather, its value is demonstrated through its performance in preclinical formulations and experimental setups where it significantly improves the solubility, stability, and controlled release profiles of associated active pharmaceutical ingredients. Studies and formulation trials indicate that derivatives and complexes formed using this amino-functionalized cyclodextrin can enhance drug loading capacity and modify pharmacokinetics, paving the way for more effective delivery systems, though the product itself is strictly intended for laboratory use and not for direct administration to humans or animals.


4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags: Mono(6-amino-6-deoxy)-β-cyclodextrin, 6-Monodeoxy-6-monoamino-beta-cyclodextrine, Amino-beta-cyclodextrin, AD-β-CD, NH2-β-CD, Mono-amino-beta-cyclodextrin, 6-Amino-6-deoxy-β-cyclodextrin, Beta-cyclodextrin amine derivative, Functionalized cyclodextrin, Drug delivery excipient


If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157

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