α-MSH
α-MSH
α-MSH
α-MSH

α-MSH

α-MSH

α-Melanocyte-Stimulating Hormone (α-MSH) is a high-purity peptide hormone widely used in skin, inflammation, and metabolic research. Its CAS number, molecular formula, molecular weight, amino acid sequence, and other key specifications are provided in the attached technical data sheet and support its reliable use in scientific applications.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
α-Melanocyte-Stimulating Hormone (α-MSH)
CAS NO.

Appearance
White to off-white lyophilized powder
Molecular Formula
C77H109N21O19S
Amino Acid Sequence
Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂
Molecular Weight
1664.9g/mol 
Purity (RP-HPLC)
≥95% (typically ≥98% available upon request)
Solubility

Soluble in water, dilute acetic acid, or phosphate buffer (pH ~7.0)

Endotoxin< 1.0 EU/mg
Biological Activity
Melanocortin receptor agonist; stimulates melanogenesis, reduces inflammation, and modulates appetite and energy homeostasis.
Storage Conditions
Store at –20°C protected from light and moisture; avoid repeated freeze‑thaw cycles.
Stock Location
Stock in USA
MOQ
1mg


1.MECHANISM OF ACTION

α-MSH functions by binding to melanocortin receptors (MCRs), particularly MC1R, MC3R, MC4R, and MC5R, activating signaling pathways that regulate pigmentation, inflammation, appetite, and energy homeostasis. This receptor interaction mediates cellular responses such as melanin synthesis and cytokine modulation.


2.PRODUCT INDICATIONS

This product is used in research on skin pigmentation, inflammatory diseases, and metabolic disorders. It is also applied in studies of appetite regulation, obesity, and potential therapeutic approaches for vitiligo, psoriasis, and other conditions influenced by melanocortin pathways.


3.CLINICAL EFFICACY OF PRODUCT

Preclinical and clinical studies have shown that α-MSH can promote melanogenesis, reduce inflammation, and modulate energy balance. Its therapeutic potential is being explored for pigmentary disorders, chronic inflammatory conditions, and metabolic syndromes, with evidence supporting its role in mediating anti-inflammatory and pigmentation effects.


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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