TECHNICAL SPECIFICATIONS
Item
| Specification
|
|---|
Product Name
| Fmoc-Ala-Ala-OH |
CAS NO.
| 87512-31-0 |
Appearance
| White to off-white crystalline powder
|
Molecular Formula
| C₂₃H₂₄N₂O₆ |
Molecular Weight
| 424.45 g/mol |
| Amino Acid Sequence | Fmoc-L-alanyl-L-alanine |
Purity (RP-HPLC)
| ≥ 98.0% |
Solubility
| Soluble in DMSO, DMF, and methanol; slightly soluble in water |
| Endotoxin | < 1.0 EU/mg
|
Biological Activity
| High-quality peptide intermediate suitable for solid-phase peptide synthesis (SPPS); preserves structural integrity for coupling reactions.
|
Storage Conditions
| Store at -20°C in a cool, dry, and well-ventilated place. Avoid repeated freeze-thaw cycles.
|
Stock Location
| Stock in USA
|
MOQ
| 1g |
1. Mechanism of Action
As a protected dipeptide building block, Fmoc-Ala-Ala-OH functions as a specialized reagent in peptide synthesis rather than possessing direct biological activity. Its chemical mechanism involves selective deprotection during solid-phase peptide synthesis: the Fmoc (9-fluorenylmethoxycarbonyl) protecting group is removed under mild basic conditions (typically 20% piperidine in DMF) to expose the α-amino group for subsequent coupling reactions.
2. Product Indications
Peptide Pharmaceutical Manufacturing – Essential intermediate for synthesizing therapeutic peptides containing alanine-rich sequences.
Structural Biology Research – Building block for creating peptides with specific secondary structure propensities.
Enzyme Substrate Development – Used in producing peptide substrates for protease and enzyme activity studies.
Biomaterial Engineering – Component in synthesizing peptides for tissue engineering and biomaterial applications.
Diagnostic Reagent Production – Intermediate for peptide-based diagnostic tools and imaging agents.
3. Clinical Efficacy of Product
While Fmoc-Ala-Ala-OH itself lacks direct clinical efficacy, peptides synthesized using this building block have demonstrated significant therapeutic potential. Alanine-rich sequences are particularly valuable in therapeutic peptides due to alanine's role in enhancing metabolic stability, promoting helical structures, and improving pharmacokinetic properties.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
