Fmoc-Ala-Ala-OH CAS NO.87512-31-0

Fmoc-Ala-Ala-OH CAS NO.87512-31-0

Fmoc-Ala-Ala-OH CAS NO.87512-31-0
Fmoc-Ala-Ala-OH CAS NO.87512-31-0
Fmoc-Ala-Ala-OH CAS NO.87512-31-0
Fmoc-Ala-Ala-OH CAS NO.87512-31-0

Fmoc-Ala-Ala-OH CAS NO.87512-31-0

Fmoc-Ala-Ala-OH CAS NO.87512-31-0

Fmoc-Ala-Ala-OH is a dipeptide building block for peptide synthesis. Features Fmoc-protected alanine linked to alanine. White powder, soluble in DMF/DMSO. Used in research to study peptide structure-activity relationships and construct bioactive peptides, offering conformational flexibility and metabolic stability.

TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Fmoc-Ala-Ala-OH
CAS NO.
87512-31-0
Appearance
White to off-white crystalline powder
Molecular Formula
C₂₃H₂₄N₂O₆
Molecular Weight
424.45 g/mol
Amino Acid SequenceFmoc-L-alanyl-L-alanine
Purity (RP-HPLC)
≥ 98.0%
Solubility

Soluble in DMSO, DMF, and methanol; slightly soluble in water

Endotoxin< 1.0 EU/mg
Biological Activity
High-quality peptide intermediate suitable for solid-phase peptide synthesis (SPPS); preserves structural integrity for coupling reactions.
Storage Conditions
Store at -20°C in a cool, dry, and well-ventilated place. Avoid repeated freeze-thaw cycles.
Stock Location
Stock in USA
MOQ
1g


1. Mechanism of Action

As a protected dipeptide building block, Fmoc-Ala-Ala-OH functions as a specialized reagent in peptide synthesis rather than possessing direct biological activity. Its chemical mechanism involves selective deprotection during solid-phase peptide synthesis: the Fmoc (9-fluorenylmethoxycarbonyl) protecting group is removed under mild basic conditions (typically 20% piperidine in DMF) to expose the α-amino group for subsequent coupling reactions.


2. Product Indications 

Peptide Pharmaceutical Manufacturing – Essential intermediate for synthesizing therapeutic peptides containing alanine-rich sequences.
Structural Biology Research – Building block for creating peptides with specific secondary structure propensities.
Enzyme Substrate Development – Used in producing peptide substrates for protease and enzyme activity studies.
Biomaterial Engineering – Component in synthesizing peptides for tissue engineering and biomaterial applications.
Diagnostic Reagent Production – Intermediate for peptide-based diagnostic tools and imaging agents.


3. Clinical Efficacy of Product

While Fmoc-Ala-Ala-OH itself lacks direct clinical efficacy, peptides synthesized using this building block have demonstrated significant therapeutic potential. Alanine-rich sequences are particularly valuable in therapeutic peptides due to alanine's role in enhancing metabolic stability, promoting helical structures, and improving pharmacokinetic properties. 


4.DELIVERY & SHIPPING

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Shipping Methods 
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