ARA290 (Cibinetide) CAS NO.1208243-50-8
ARA290 (Cibinetide) CAS NO.1208243-50-8
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | ARA290 (Cibinetide) |
| CAS NO. | 1208243 - 50 - 8 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C51H84N16O21 |
| Molecular Weight | 1257.31 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | ARA290 exhibits cytoprotective, anti - inflammatory, and tissue - regenerative properties. In pre - clinical and some clinical studies, it has demonstrated potential in treating various diseases and conditions related to tissue damage, inflammation, and oxidative stress |
| Storage Conditions | Store at - 20°C in a dry and dark environment. Avoid repeated freeze - thaw cycles to maintain product stability. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
ARA290 functions by binding to the erythropoietin receptor (EPOR) and its associated signaling complexes. This binding activates downstream signaling pathways, including the JAK2 - STAT5 pathway. These pathways play crucial roles in cell survival, proliferation, and differentiation. By modulating these signaling cascades, ARA290 exerts its cytoprotective, anti - inflammatory, and tissue - regenerative effects. It can protect cells from various forms of stress, such as oxidative stress and ischemia - reperfusion injury, and also reduce the production of pro - inflammatory cytokines.
2.PRODUCT INDICATIONS
Renal Diseases: Investigated for reducing inflammation and promoting tissue repair in acute/chronic kidney injury.
Cardiovascular Disorders: Potential use in myocardial infarction and heart failure to protect cardiac cells, improve contractility, and reduce post-infarction scar formation.
Neurological Conditions: Explored for aiding neural tissue recovery and mitigating neuroinflammation in disorders like stroke or traumatic brain injury.
Metabolic Diseases: Studied for alleviating oxidative stress and tissue damage in metabolic syndrome-related complications.
3.CLINICAL EFFICACY OF PRODUCT
In renal injury models: Reduced kidney damage progression, improved glomerular filtration rate (GFR), and decreased inflammatory cell infiltration.
In cardiovascular models: Enhanced cardiac function and reduced infarct size after myocardial infarction.
In neurological models: Promoted neuronal survival and reduced neuroinflammatory markers
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Nov 05, 26
Global Market Analysis and Oxandrolone 50mg Price Guide
For B2B pharmaceutical buyers and researchers, understanding the oxandrolone 50mg price involves analyzing more than just a numerical value; it requires a comprehensive look at API purity, synthesis methods, and global supply chain stability. As a specialized anabolic steroid derivative, the cost is heavily influenced by the quality of raw materials and the rigor of the laboratory testing involved in the production process. This article explores the economic and technical variables that dictate market pricing for this specific compound. In the context of the global API market, pricing volatility is often tied to regulatory shifts in key manufacturing hubs
Nov 04, 26
How to Select High Purity Alisol C CAS 30489271 for Laboratory Research
High Purity Alisol C CAS 30489271 is suited to laboratories using Alisol C as a triterpenoid reference standard in metabolic, hepatology, pharmacology, HPLC/MS, botanical-extract, or selected cell-line research. We explain the application fit and the identity, purity, physical form, solvent, endotoxin, storage, quantity, and batch-record checks to make before ordering.
Nov 02, 26
Reliable Oxandrolone Supplier for High Purity Pharmaceutical APIs
When sourcing high-purity pharmaceutical ingredients for endocrine or cardiovascular research, the reliability of the supply chain is as critical as the chemical purity itself. For laboratories and manufacturers seeking a dependable oxandrolone supplier, the focus must extend beyond simple certificates of analysis to encompass consistent batch-to-batch stability and strict adherence to GMP standards. Whether the requirement is for small-scale pilot studies or large-scale industrial production, the ability to trace materials from raw synthesis to final lyophilized powder ensures the integrity of the resulting clinical or research data.