Prepro-Atrial Natriuretic Factor (104-123) (human) CAS NO.112160-83-5

Prepro-Atrial Natriuretic Factor (104-123) (human) (CAS NO. 112160-83-5) is a synthetic, 20-amino acid peptide fragment corresponding to residues 104-123 of the human prepro-ANP precursor protein. This high-purity peptide represents a segment of the prohormone's mid-region and is a specialized research tool for studying atrial natriuretic peptide (ANP) biosynthesis, processing, and potential ancillary biological functions distinct from the mature ANP hormone.

Send Email

Download

TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Prepro-Atrial Natriuretic Factor (104-123) (human)
CAS NO.	112160-83-5
Appearance	White to off-white lyophilized powder
Molecular Formula	C94H171N31O28
Molecular Weight	2183.6/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in water (≥1 mg/mL), 0.1% TFA in water, or dilute acetic acid
Endotoxin	≤1.0 EU/mg
Biological Activity	This peptide segment is a prohormone region of ANF and does not exhibit direct vasoactive activity.
Storage Conditions	Store at ≤ -20°C in a dry, dark environment.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

This peptide is derived from the prepro-ANP sequence that lies outside the region encoding the mature, circulating ANP (99-126). Its precise biological activity, if any, is not related to classical NPR-A activation. Its primary research utility lies in its role as a defined antigenic sequence. It may be involved in intracellular processing or act as a precursor for other, less-characterized peptide fragments.

2.PRODUCT INDICATIONS

This product is indicated for specialized research in cardiovascular endocrinology, peptide biochemistry, and assay development. Key applications include: generating specific antibodies for measuring ANP precursor fragments (e.g., pro-ANP, NT-proANP) in immunoassays, studying the proteolytic processing and cellular trafficking of prepro-ANP, investigating potential biological activities of non-mature ANP regions, and serving as a reference standard in mass spectrometry or chromatographic studies of ANP-related peptides.

3.CLINICAL EFFICACY OF PRODUCT

Prepro-ANF (104-123) is a research reagent with no direct therapeutic application. Its clinical "efficacy" is indirect but significant. Antibodies raised against this and similar pro-region peptides are fundamental to clinical diagnostic assays that measure N-terminal pro-atrial natriuretic peptide (NT-proANP).

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.