Name: Prepro-Atrial Natriuretic Factor (104-123) Human Peptide CAS 112160-83-5
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Prepro-Atrial Natriuretic Factor (104-123) (human) CAS NO.112160-83-5

Prepro-Atrial Natriuretic Factor (104-123) (human) (CAS NO. 112160-83-5) is a synthetic, 20-amino acid peptide fragment corresponding to residues 104-123 of the human prepro-ANP precursor protein. This high-purity peptide represents a segment of the prohormone's mid-region and is a specialized research tool for studying atrial natriuretic peptide (ANP) biosynthesis, processing, and potential ancillary biological functions distinct from the mature ANP hormone.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Prepro-Atrial Natriuretic Factor (104-123) (human)
CAS NO.	112160-83-5
Appearance	White to off-white lyophilized powder
Molecular Formula	C94H171N31O28
Molecular Weight	2183.6/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in water (≥1 mg/mL), 0.1% TFA in water, or dilute acetic acid
Endotoxin	≤1.0 EU/mg
Biological Activity	This peptide segment is a prohormone region of ANF and does not exhibit direct vasoactive activity.
Storage Conditions	Store at ≤ -20°C in a dry, dark environment.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

This peptide is derived from the prepro-ANP sequence that lies outside the region encoding the mature, circulating ANP (99-126). Its precise biological activity, if any, is not related to classical NPR-A activation. Its primary research utility lies in its role as a defined antigenic sequence. It may be involved in intracellular processing or act as a precursor for other, less-characterized peptide fragments.

2.PRODUCT INDICATIONS

This product is indicated for specialized research in cardiovascular endocrinology, peptide biochemistry, and assay development. Key applications include: generating specific antibodies for measuring ANP precursor fragments (e.g., pro-ANP, NT-proANP) in immunoassays, studying the proteolytic processing and cellular trafficking of prepro-ANP, investigating potential biological activities of non-mature ANP regions, and serving as a reference standard in mass spectrometry or chromatographic studies of ANP-related peptides.

3.CLINICAL EFFICACY OF PRODUCT

Prepro-ANF (104-123) is a research reagent with no direct therapeutic application. Its clinical "efficacy" is indirect but significant. Antibodies raised against this and similar pro-region peptides are fundamental to clinical diagnostic assays that measure N-terminal pro-atrial natriuretic peptide (NT-proANP).

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
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Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
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Main Method: International Air Freight

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