Oleandrin CAS NO.465-16-7

Oleandrin CAS NO.465-16-7

Oleandrin CAS NO.465-16-7

Oleandrin CAS NO.465-16-7

Oleandrin CAS NO.465-16-7

Oleandrin is a highly bioactive cardenolide compound primarily extracted from the leaves, stems, and flowers of Nerium oleander(common oleander), widely recognized for its potent pharmacological actions including antitumor and antiviral properties, making it a valuable chemical probe and potential therapeutic agent for cutting-edge biomedical research aimed at targeting refractory tumors, viral infections, and inflammatory diseases.


TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Oleandrin
CAS NO.
465-16-7
Appearance
White to off-white crystalline powder
Molecular Formula
C₃₂H₄₈O₉
Molecular Weight
576.72 g/mol
Amino Acid Sequence
Not applicable
Purity (RP-HPLC)
≥98.0%
Solubility
Soluble in DMSO, methanol, and ethanol; insoluble in water
Endotoxin
< 1 EU/mg
Biological Activity
Potent cardiac glycoside with significant anti-tumor, anti-inflammatory, antiviral, and immunomodulatory effects; exhibits high affinity for Na⁺/K⁺-ATPase enzyme
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Location
USA / Germany / China (optional, based on actual stock)
MOQ
1 mg


1.Mechanism of Action

Oleandrin exerts its diverse biological effects mainly by binding to and inhibiting the Na⁺/K⁺-ATPase pump on cell membranes, leading to increased intracellular calcium levels, disruption of cellular ion homeostasis, activation of pro-apoptotic signaling pathways such as JNK and p38 MAPK, and modulation of inflammatory cytokine production, thereby inducing cytotoxic effects in cancer cells while also demonstrating specific antiviral activity through interference with viral entry and replication mechanisms.

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2.Product Indications

This compound is specifically indicated for use in preclinical and early-stage clinical research investigations focusing on oncology, particularly for studying drug resistance reversal and targeted cytotoxicity in various carcinoma cell lines, as well as for virology studies exploring antiviral efficacy against enveloped viruses, along with applications in cardiovascular pharmacology research examining ionotropic effects and neuroprotective studies exploring anti-inflammatory mechanisms in neurodegenerative disease models.

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3.Clinical Efficacy of Product

Although still under extensive investigation, emerging preclinical data suggest that Oleandrin holds significant promise in effectively inhibiting tumor cell proliferation, reducing angiogenesis, and suppressing metastasis across multiple cancer types, while concurrently exhibiting robust antiviral efficacy in vitro and in vivo models, demonstrating its potential as a multifunctional therapeutic candidate for treating aggressive cancers and viral pathogens, though comprehensive clinical efficacy data in human populations remains limited and requires further validation.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

Osthenol CASNO.484-14-0


5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.


Osthenol CASNO.484-14-0


Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


HotTags:Oleandrin, #CardiacGlycoside, #CancerResearch, #Antiviral, #NaKATPaseInhibitor, #Phytochemical, #BioactiveCompound, #PreclinicalResearch, #NaturalProduct, #DrugDiscovery

If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:85270846510


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