Oleandrin CAS NO.465-16-7

Oleandrin CAS NO.465-16-7

Oleandrin CAS NO.465-16-7

Oleandrin CAS NO.465-16-7

Oleandrin CAS NO.465-16-7

Oleandrin is a highly bioactive cardenolide compound primarily extracted from the leaves, stems, and flowers of Nerium oleander(common oleander), widely recognized for its potent pharmacological actions including antitumor and antiviral properties, making it a valuable chemical probe and potential therapeutic agent for cutting-edge biomedical research aimed at targeting refractory tumors, viral infections, and inflammatory diseases.


TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Oleandrin
CAS NO.
465-16-7
Appearance
White to off-white crystalline powder
Molecular Formula
C₃₂H₄₈O₉
Molecular Weight
576.72 g/mol
Amino Acid Sequence
Not applicable
Purity (RP-HPLC)
≥98.0%
Solubility
Soluble in DMSO, methanol, and ethanol; insoluble in water
Endotoxin
< 1 EU/mg
Biological Activity
Potent cardiac glycoside with significant anti-tumor, anti-inflammatory, antiviral, and immunomodulatory effects; exhibits high affinity for Na⁺/K⁺-ATPase enzyme
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Location
USA / Germany / China (optional, based on actual stock)
MOQ
1 mg


1.Mechanism of Action

Oleandrin exerts its diverse biological effects mainly by binding to and inhibiting the Na⁺/K⁺-ATPase pump on cell membranes, leading to increased intracellular calcium levels, disruption of cellular ion homeostasis, activation of pro-apoptotic signaling pathways such as JNK and p38 MAPK, and modulation of inflammatory cytokine production, thereby inducing cytotoxic effects in cancer cells while also demonstrating specific antiviral activity through interference with viral entry and replication mechanisms.

upload/attachment/image/202605/15/1778831678a6f84bfa5f959f8fd0e89fc965e97759_local.pngupload/attachment/image/202605/15/177883168512f317c529d7ab99cc0a82c0bedb3cbc_local.png

2.Product Indications

This compound is specifically indicated for use in preclinical and early-stage clinical research investigations focusing on oncology, particularly for studying drug resistance reversal and targeted cytotoxicity in various carcinoma cell lines, as well as for virology studies exploring antiviral efficacy against enveloped viruses, along with applications in cardiovascular pharmacology research examining ionotropic effects and neuroprotective studies exploring anti-inflammatory mechanisms in neurodegenerative disease models.

upload/attachment/image/202605/15/17788316959c34a6fc8347a03022c951ea8f5e2d55_local.png

3.Clinical Efficacy of Product

Although still under extensive investigation, emerging preclinical data suggest that Oleandrin holds significant promise in effectively inhibiting tumor cell proliferation, reducing angiogenesis, and suppressing metastasis across multiple cancer types, while concurrently exhibiting robust antiviral efficacy in vitro and in vivo models, demonstrating its potential as a multifunctional therapeutic candidate for treating aggressive cancers and viral pathogens, though comprehensive clinical efficacy data in human populations remains limited and requires further validation.

upload/attachment/image/202605/15/17788317098deb43cc544f227b74d637d08dc38c5e_local.png

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

Osthenol CASNO.484-14-0


5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.


Osthenol CASNO.484-14-0


Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


HotTags:Oleandrin, #CardiacGlycoside, #CancerResearch, #Antiviral, #NaKATPaseInhibitor, #Phytochemical, #BioactiveCompound, #PreclinicalResearch, #NaturalProduct, #DrugDiscovery

If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:85270846510


Analyzing Oxandrolone Side Effects and Selective Peptides
Jun 13, 26
Analyzing Oxandrolone Side Effects and Selective Peptides
Understanding the nuances of pharmaceutical interactions and potential oxandrolone side effects is critical for researchers and clinicians aiming to optimize patient outcomes in metabolic and cardiovascular studies. While many chemical compounds offer profound therapeutic potential, the ability to distinguish between intended biological activity and adverse reactions ensures a higher standard of safety and efficacy in translational medicine. On a global scale, the demand for high-purity research peptides and active pharmaceutical ingredients has surged as scientific communities seek to mitigate the risks associated with legacy treatments.
Clinical Guide to Oxandrolone Uses and Metabolic Benefits
Jun 12, 26
Clinical Guide to Oxandrolone Uses and Metabolic Benefits
In the contemporary landscape of metabolic medicine and pharmaceutical research, understanding the diverse oxandrolone uses is pivotal for clinicians and researchers alike. While the industry continues to evolve, the demand for high-purity active pharmaceutical ingredients APIs remains the cornerstone of effective therapeutic outcomes, particularly in treating muscle wasting and metabolic dysfunction. The global shift toward personalized medicine has highlighted the importance of specific androgenic agents and GLP-1 agonists in managing complex patient profiles. By analyzing the systemic impact of these compounds, the pharmaceutical sector can better address the needs of patients recovering from severe trauma or managing chronic endocrine imbalances.
Salmon Calcitonin and oxandrolone use for Bone Health
Jun 11, 26
Salmon Calcitonin and oxandrolone use for Bone Health
The global pharmaceutical landscape is increasingly focusing on the precision of bone metabolism regulation, where the strategic oxandrolone use is often discussed in the context of anabolic recovery, yet the specialized application of Salmon Calcitonin provides a critical alternative for systemic calcium management. Understanding the nuanced differences between anabolic agents and calcitonin-based therapies is essential for healthcare providers aiming to treat severe osteoporosis and hypercalcemia. In the realm of chemical raw material manufacturing, the production of high-purity peptides like Salmon Calcitonin represents a pinnacle of biotechnological achievement. While some research focuses on oxandrolone use for muscle wasting, Salmon Calcitonin targets the osteoclast directly,

If you are interested in our products, you can choose to leave your information here, and we will be in touch with you shortly.