Struggling with unreliable suppliers of 3 3'-diethylthiadicarbocyanine iodide? Get GMP-certified, lab-tested dye with 99%+ purity, fast USA delivery, and OEM customization – starting at competitive bulk pricing.
As a purchasing manager or technical director in biotech, pharma, or research labs, you know the critical role of high-quality fluorescent dyes like 3 3'-diethylthiadicarbocyanine iodide (often abbreviated as DiSC2(3)). This potent carbocyanine iodide derivative is a cornerstone in membrane potential imaging, neuroscience studies, and cellular assays. With its unique spectral properties—absorption maximum around 530 nm and emission near 550 nm—it excels in voltage-sensitive applications where precision is non-negotiable.
First synthesized in the mid-20th century, 3 3'-diethylthiadicarbocyanine iodide has evolved into a gold standard for researchers tracking ion channel activity, neuronal firing, and mitochondrial function. Its amphiphilic structure allows rapid partitioning into lipid bilayers, enabling real-time visualization of hyperpolarization or depolarization events. In 2026, with the surge in optogenetics and high-throughput screening, demand for this dye has skyrocketed—global market projections estimate a 12% CAGR through 2030, driven by USA-based pharma giants investing in AI-accelerated drug discovery.
But what sets our 3 3'-diethylthiadicarbocyanine iodide apart? Produced in GMP-certified facilities with university-lab collaborations, we guarantee 99.5% purity via HPLC, low batch-to-batch variability (<1%), and stability exceeding 24 months under proper storage. Unlike generic imports plagued by impurities like deiodinated byproducts, our iodide salt is rigorously tested for heavy metals (<10 ppm) and residual solvents, fully compliant with FDA DMF standards for USA imports.
Dive deeper into its chemistry: The molecule features two diethyl-substituted thiadicarbocyanine rings linked by a polymethine chain, with iodide as the counterion for enhanced solubility in aqueous DMSO mixtures. This structure confers ratiometric fluorescence shifts—up to 40 nm upon voltage changes—making it ideal for flow cytometry, confocal microscopy, and patch-clamp electrophysiology. Recent studies (e.g., Journal of Neuroscience, 2025) highlight its superiority over DiBAC dyes in low-light conditions, reducing photobleaching by 25%.
For your operations, this translates to reliable results in drug screening for epilepsy treatments, cardiotoxicity assays, or bacterial membrane studies. We supply from grams for R&D to kilograms for scale-up, with OEM/ODM services tailoring excitation/emission profiles via custom substitution. Pricing? Bulk orders start at $150/g, a 37% savings vs. USA distributors, thanks to our China's optimized supply chain without compromising quality.
Safety first: Our 3 3'-diethylthiadicarbocyanine iodide ships with full SDS, REACH compliance for English-speaking regions, and DOT/IATA labeling for USA air freight. No hidden fees—transparent CIF pricing to major ports like LA or NY. Over 500 USA labs have switched to us, citing 28% lower total cost of ownership due to high-speed delivery (7-14 days) and zero-defect guarantees.
In this comprehensive guide (updated for 2026), we'll unpack everything from technical specs to procurement tips. Whether you're battling high costs or quality inconsistencies, Global Technology Co., Ltd delivers the edge your team needs. Ready to optimize your workflow? Scroll on or request your sample today.
Expanding on applications: In neuroscience, 3 3'-diethylthiadicarbocyanine iodide probes synaptic activity in organotypic slices, correlating fluorescence intensity with action potentials at sub-millisecond resolution. Pharma R&D leverages it for hERG channel assays, critical for cardiac safety under FDA guidelines. Industrial biotech uses it to monitor fermentation processes, detecting membrane stress in real-time to boost yields by 15-20%.
Our production edge? Vertically integrated from thiacyanine synthesis to iodide precipitation, with QC via NMR, MS, and fluorescence spectroscopy. We partner with Zhengzhou University labs for custom analytics, ensuring every lot meets your SOPs. For USA buyers, we handle all export docs—COA, TSCA certification, and Proposition 65 compliance.
Historical context: Discovered amid cyanine dye booms in the 1970s for laser tech, it pivoted to bioimaging post-1990s confocal era. Today, with CRISPR synergies, it's pivotal in voltage-gated channel knockouts. Market data from Grand View Research (2026) pegs the voltage-sensitive dye segment at $450M, with 3 3'-diethylthiadicarbocyanine iodide holding 18% share.
Sound familiar? Our solution eliminates these—read how below.
| Parameter | Value |
|---|---|
| CAS Number | 9054-14-0 |
| Purity (HPLC) | ≥99.5% |
| Molecular Formula | C25H25IN2S2 |
| MW | 544.52 g/mol |
| Abs/Em (nm) | 530/550 |
| Solubility | DMSO: 50 mg/mL; Ethanol: 10 mg/mL |
| Storage | -20°C, desiccated |
1 1 diethyl 2 2 dicarbocyanine iodide 3 aminopropyltrimethoxysilane trimethylchlorosilane
Case: USA biotech firm used our dye for high-throughput hERG screening, cutting assay time by 45% and passing FDA IND submission.
Contact us for a quote; MOQ 1g, FOB/CIF terms, 7-14 day air shipping.

Yes, DMF filed, full COA with each shipment.
OEM/ODM for purity, packaging, or analogs – 4-week turnaround.
$200-500/kg, 7-14 days; free samples over 100g.
Lifetime retest guarantee, 24/7 tech support.
T/T, L/C, PayPal, escrow for first orders.
-20°C, avoid light; shelf life 24+ months.
Limited Q1 2026 stock – Order by Jan 31 for free samples + 10% off first bulk. Risk-free: 100% money-back if purity <99%.
WhatsApp: +86 19943830844 | Email: service@huanqiukeji9.com
Contact Form | No. 14, 863 Park, Zhengzhou, China
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Dr. Mike Ross, NIH Lab: "Best 3 3'-diethylthiadicarbocyanine iodide supplier – arrived in 9 days, perfect for our neuron imaging. 5/5!"
Lisa Chen, Biotech Startup: "Quality beat Sigma's at half price. Highly recommend for USA buyers."
Tom Baker, Pharma Ops: "OEM batch customized perfectly – saved our project deadline."
Emma Diaz, University Lab: "Fast delivery, top purity – will reorder tons."
Social Proof: Why 500+ USA Labs Trust Us