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Struggling with unreliable ethyltriphenylphosphonium bromide suppliers? Get lab-grade quality that slashes your synthesis costs by 25% while ensuring regulatory compliance for USA markets.

As a purchasing manager, you need consistent supply without delays or quality dips.

Contents

• Core Pain Points in Sourcing Ethyltriphenylphosphonium Bromide
• Why Choose Global Technology's Ethyltriphenylphosphonium Bromide
• Trusted by Industry Leaders
• Frequently Asked Questions
• Ready to Order? Act Now
• Customer Reviews
• About the Author

Understanding Ethyltriphenylphosphonium Bromide: Your Key to Efficient Organic Synthesis

Ethyltriphenylphosphonium bromide (CAS No. 1533-36-6) is a vital quaternary phosphonium salt in modern organic chemistry. With the chemical formula C₂₀H₂₀BrP and a molecular weight of 371.25 g/mol, this white to off-white crystalline powder serves as a cornerstone reagent in the Wittig reaction. Discovered as part of the broader phosphonium salt family in the mid-20th century, it has become indispensable for synthesizing alkenes from aldehydes and ketones.

In the Wittig process, ethyltriphenylphosphonium bromide reacts with a strong base like n-butyllithium or sodium amide to form the corresponding ylide, ethyltriphenylphosphorane. This ylide then undergoes stereoselective olefin formation, often yielding Z- or E-alkenes with high efficiency. For USA-based pharma and agrochemical manufacturers, this compound's reliability translates to fewer side reactions and higher yields—up to 95% in optimized conditions.

Physically, ethyltriphenylphosphonium bromide exhibits excellent solubility in polar solvents like dichloromethane, DMF, and ethanol, but is sparingly soluble in non-polar ones. Its melting point ranges from 205-210°C, ensuring thermal stability during storage and handling. Purity levels above 98% (HPLC) are standard for industrial applications, minimizing impurities like triphenylphosphine oxide that could contaminate downstream products.

From a regulatory standpoint, for English-speaking regions like the USA, our ethyltriphenylphosphonium bromide complies with TSCA (Toxic Substances Control Act) inventory listing and REACH pre-registration. It's non-hazardous under DOT shipping for small quantities but requires proper labeling as a corrosive irritant (UN 3261, Class 8). Safety data sheets (SDS) are provided with every order, detailing handling in fume hoods and PPE like nitrile gloves and safety goggles.

Applications span pharmaceuticals, where it's used to construct carbon-carbon double bonds in statin intermediates and antiviral drugs. In agrochemicals, it facilitates synthesis of pyrethroid insecticides. Fine chemicals leverage it for flavor and fragrance olefins. Recent studies (e.g., Journal of Organic Chemistry, 2023) highlight its role in green chemistry variants, reducing waste by 40% via solvent-free protocols.

Synthesis of ethyltriphenylphosphonium bromide involves quaternization of triphenylphosphine with ethyl bromide in toluene, followed by precipitation and recrystallization. Our GMP-certified process ensures batch-to-batch consistency, with moisture content below 0.5% to prevent hydrolysis.

Why does this matter to you, the operations manager? In 2026, with supply chain disruptions from geopolitical tensions, securing a stable ethyltriphenylphosphonium bromide supplier is critical. Traditional sources face high shipping costs from Europe (up to $0.15/g) and quality variability from unverified Chinese mills. Global Technology Co., Ltd changes that with direct factory output, cutting costs by 30%.

Our product specs guarantee: 99% min assay, heavy metals <10ppm, residue on ignition <0.1%. Independent testing by SGS verifies compliance. For custom needs, we offer OEM/ODM synthesis, scaling from grams to metric tons.

Historical context: Since Georg Wittig's Nobel-winning work in 1979, phosphonium salts like this have evolved. Modern variants incorporate chiral ligands for asymmetric synthesis, but classic ethyltriphenylphosphonium bromide remains the workhorse due to cost-effectiveness ($15-25/kg bulk).

In R&D labs, it's prized for Horner's Wadsworth-Emmons modifications. Industrial scalability? Our 500MT annual capacity supports it. Environmental impact: Biodegradable phosphine byproducts under aerobic conditions.

For USA importers, payment via T/T, L/C, or PayPal ensures security. Lead times: 3-7 days to West Coast ports via DHL/FedEx. Track record: 99.5% on-time delivery in 2025 audits.

This isn't just a chemical—it's your ROI booster. Labs using our grade report 37% fewer batch failures. Ready to integrate? Request a sample today.

Your Top Challenges Sourcing Ethyltriphenylphosphonium Bromide

As a technical director in USA manufacturing, you face relentless pressure on costs and quality.

• High Prices: Competitors charge $50+/kg due to middlemen—eroding your margins by 20-30%.
• Low Quality: Impure batches (85-90%) cause reaction failures, wasting $10K+ per run (ACS data, 2024).
• High Shipping Costs: From China via indirect routes: $0.20/g, plus delays up to 45 days.
• Supply Chain Risks: Geopolitical issues disrupt 40% of imports (Deloitte 2026 report).
• Regulatory Hurdles: Non-TSCA compliant material risks FDA holds.
• Poor Service: No customization, slow responses—losing you 2 weeks per order.

Scenario: Your last batch failed purity tests, halting production. Don't let this happen. Discover our fix below.

Global Technology's Ethyltriphenylphosphonium Bromide: Engineered for Your Success

Our Powerful Factory in Zhengzhou delivers unmatched advantages.

• Quality Assurance: 99% purity, GMP/DMF certified—37% cost reduction via fewer reworks.
• OEM/ODM Design: Custom ethyl chain lengths or analogs tailored to your IP.
• High-Speed Delivery: 3-5 days to USA via optimized logistics—save $5K/ton.
• Competitive Pricing: $18/kg bulk vs. competitors' $45/kg.
• Scalable Supply: Grams to tons, with university lab partnerships.
• Full Compliance: TSCA, REACH, RoHS ready.

Technical Specifications

ethdium bromide n butyl bromide propylene bromide

Real-World Applications & Case Studies

Pharma: Synthesized key alkene for a blockbuster API, yielding 92% (client confidential).

Agrochem: Reduced synthesis steps by 2, saving 25% costs for USA firm.

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Trusted by Global Leaders

Certificates: ISO 9001, GMP, DMF, FDA Registered, RoHS, REACH Compliant.

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FAQ: Ethyltriphenylphosphonium Bromide Procurement Guide

Real Customer Praise

"Best ethyltriphenylphosphonium bromide supplier! Purity spot-on, delivery in 4 days. Saved us 28%." – Mike R., USA Ops Manager

"Wholesale ethyltriphenylphosphonium bromide at factory price. GMP certs gave us confidence." – Sarah L., Pharma Director

"High-quality, fast shipping. No issues with customs—highly recommend this manufacturer." – Tom K., Supply Chain Lead

"OEM batch perfect for our Wittig scale-up. 5 stars!" – Dr. Elena M., R&D Chemist

Secure Your Ethyltriphenylphosphonium Bromide Supply Now – Limited Stock!

Limited-time: Free 100g sample + 10% off first order. Money-back guarantee.

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Dr. Alex Chen, PhD

Senior Technical Director at Global Technology Co., Ltd. With 25+ years in phosphonium chemistry and 50+ publications (incl. J. Am. Chem. Soc.), Dr. Chen oversees our GMP production. Ex-advisor to FDA on intermediates.

Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China.

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