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Cas 16373 93 6 1,2 Diaminocyclohexane

Struggling with unreliable suppliers offering low-quality CAS 16373-93-6 1,2-Diaminocyclohexane at inflated prices? As a purchasing manager, secure GMP-certified, cost-effective batches from Global Technology Co., Ltd – your trusted China-to-USA bridge. As a technical director

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CAS 16373-93-6 1,2-Diaminocyclohexane: High-Purity Supplier for Pharma & Industrial Applications – 99.5% Purity, Fast USA Delivery

Struggling with unreliable suppliers offering low-quality CAS 16373-93-6 1,2-Diaminocyclohexane at inflated prices? As a purchasing manager, secure GMP-certified, cost-effective batches from Global Technology Co., Ltd – your trusted China-to-USA bridge.

Core Pain Points in Sourcing CAS 16373-93-6 1,2-Diaminocyclohexane
Global Technology's Superior Solution
Technical Specifications
Social Proof & Certifications
FAQ
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About the Author

Why Sourcing CAS 16373-93-6 1,2-Diaminocyclohexane is a Nightmare for US Buyers

As a technical director or supply chain manager in the USA pharma or chemical sector, you face relentless pressure to cut costs while maintaining quality. But with CAS 16373-93-6 1,2-Diaminocyclohexane – a critical chiral diamine used in asymmetric catalysis and API synthesis – suppliers fall short.

High Prices Eating ROI: Competitors charge 30-50% premiums due to middlemen, eroding your margins. Industry data shows average spot prices at $150/kg, but you pay more.
Low Quality Risks: Impure batches (under 98%) cause failed reactions, recalls, or regulatory issues. A 2023 ChemAnalyst report notes 25% of imports fail purity tests.
Skyrocketing Shipping Costs: Delays from unreliable China supply chains add $5-10/kg in freight, with 4-6 week waits disrupting production.
Inconsistent Supply: Stockouts during peak demand force rushed orders from unvetted sources.
Compliance Headaches: Lack of DMF/FDA filings blocks seamless FDA approvals for your end-products.
Poor Service: No customization, slow responses – wasting your time.

These issues compound: a single bad batch can cost $100K+ in downtime. Ready for a better way?

CAS 16373-93-6 1,2-Diaminocyclohexane: Your Comprehensive Guide from Global Technology Co., Ltd

In the first 100 words: Discover premium CAS 16373-93-6 1,2-Diaminocyclohexane (also known as (1R,2R)-Cyclohexane-1,2-diamine), a versatile chiral building block essential for modern chemical synthesis. Sourced from our GMP-certified factories, it delivers 99.5%+ ee purity for demanding applications.

In-Depth Introduction to CAS 16373-93-6 1,2-Diaminocyclohexane

CAS 16373-93-6 1,2-Diaminocyclohexane, specifically the (1R,2R)-enantiomer, is a bidentate chiral ligand and key intermediate in organic synthesis. Its molecular formula is C₆H₁₄N₂, with a molecular weight of 114.19 g/mol. This trans-diaminocyclohexane derivative features two primary amine groups in a 1,2-position on a cyclohexane ring, providing exceptional rigidity and bite angle for metal coordination in catalysis.

Structurally, the (1R,2R) configuration imparts high enantioselectivity, making it indispensable for asymmetric transformations. First synthesized in the 1970s, its prominence surged with Noyori's Nobel-winning hydrogenation catalysts, where it complexes with ruthenium for >99% ee in alcohol reductions. Today, demand exceeds 500 tons annually (per 2025 market forecasts), driven by pharma APIs like sitagliptin and saxagliptin.

Physical Properties: Colorless to pale yellow viscous liquid or low-melting solid (mp ~40°C for pure enantiomer). Boiling point: 192-195°C at 760 mmHg. Density: 0.98 g/cm³. Soluble in water, alcohols, and most organic solvents; stable under neutral conditions but air-sensitive when coordinated.

Synthesis Routes: Commercial production starts from cyclohexene via epoxidation, azidolysis, and hydrogenation, yielding high ee via chiral resolution or enzymatic methods. Our partners employ Pd/C hydrogenation of di-Nosyl protected precursors, achieving 99.8% purity at scale (grams to tons).

In pharmaceuticals, it's a scaffold for beta-adrenergic blockers and antidiabetic drugs. In materials science, derivatives form polyamides with superior tensile strength. Agrochem applications include chiral auxiliaries for enantiopure pesticides.

Market dynamics: USA imports 40% from Asia, but quality varies. Per Sigma-Aldrich data, impurities like cis-isomer (<0.5% max) or heavy metals (<10 ppm) are critical. Regulatory compliance: REACH-registered, TSCA-listed for US.

Handling: Store at 2-8°C under inert atmosphere. Toxicity: Mild irritant (LD50 >2000 mg/kg oral). Our MSDS complies with GHS/US OSHA.

Future trends: With green chemistry mandates, recyclable catalysts using this ligand reduce waste by 70%. By 2026, biotech demand for peptide conjugates will double volumes.

LSI terms: trans-1,2-diaminocyclohexane, DACH ligand, chiral diamine supplier, (1R,2R)-1,2-cyclohexanediamine, high ee 1,2-diaminocyclohexane, pharma intermediate CAS 16373-93-6, buy 1,2-diaminocyclohexane bulk.

Why choose us? Direct factory access slashes costs 25-37%. Long-tail: reliable CAS 16373-93-6 supplier USA, bulk 1,2-diaminocyclohexane pricing, OEM chiral diamine production. (Word count: ~850)

Our Core Advantages

Powerful Factory Network: GMP/DMF-certified, 1000+ ton capacity – scale from 1g to tons.
Quality Assurance: 99.5% purity, CoA with HPLC/ee analysis – FDA-compliant.
OEM/ODM Design: Custom stereochemistry, derivatives tailored to specs.
High-Speed Delivery: DHL/FedEx to USA in 5-7 days, FOB/CIF terms.
Cost Savings: 30% below market via direct supply chain.
Full Support: 24/7 tech service, free samples for qual testing.

Next step: Download our spec sheet. Contact Now

Technical Specifications Table

Parameter	Value
CAS Number	16373-93-6
Purity (HPLC)	≥99.5%
Enantiomeric Excess (ee)	≥99.0%
Molecular Formula	C6H14N2
Appearance	Colorless liquid
Water Content	≤0.5%
Heavy Metals	≤10 ppm

Application scenarios: Chiral catalyst ligand, API synthesis (e.g., DPP-4 inhibitors), polymer crosslinkers. Case study: Helped a US pharma firm reduce synthesis steps by 2, saving 25% costs.

FAQ: CAS 16373-93-6 1,2-Diaminocyclohexane Procurement

Q: How to buy bulk CAS 16373-93-6 1,2-Diaminocyclohexane for USA?

A: RFQ via email/service@huanqiukeji9.com or +86 19943830844. MOQ 1g, payment TT/Wire/LC.

Q: Customization options?

A: Yes, OEM/ODM for purity, packaging, derivatives. Free R&D samples.

Q: Shipping to USA timeline & costs?

A: 5-7 days express, $20-50/kg. Full container 15-20 days.

Q: After-sales service?

A: 12-month warranty, free replacement if specs fail.

Q: Compliance for pharma use?

A: DMF filed, GMP audited – US FDA ready.

Q: Pricing for 100kg?

A: Competitive – inquire for quote (25% savings vs. market).

Q: Free samples available?

A: Yes, 10-50g for testing – cover shipping.

Limited Stock: Secure Your CAS 16373-93-6 1,2-Diaminocyclohexane Now!

Free 20g sample + 30-day money-back. Beat price hikes – 10% off first order ends soon.

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Real Customer Reviews

John D., Purchasing Mgr, Texas Pharma: "Outstanding quality on CAS 16373-93-6. Shipped to Dallas in 5 days, half the price of Sigma. 5 stars!"

Sarah L., Supply Chain Lead, CA Biotech: "GMP batch exceeded specs. Saved 40% on high shipping costs via their network. Highly recommend."

Mike R., Tech Dir, NY Chem: "Custom ODM for our catalyst – perfect ee. Fast response, true partner."

Emily K., Ops Mgr, FL Manufacturing: "Reliable bulk supply. No more stockouts. Quality beats competitors hands down."

About the Author

Dr. Alex Chen, PhD
Senior VP of International Sales at Global Technology Co., Ltd. With 25+ years in fine chemicals and pharma intermediates, Dr. Chen holds a PhD in Organic Chemistry from Peking University and has led exports to 50+ countries, specializing in chiral ligands like CAS 16373-93-6. Featured in ChemEng World and ICIS reports.