As a purchasing manager or technical director in biotech/pharma, you're facing high costs, inconsistent quality, and delays in sourcing D-Melibiose for enzyme assays and carbohydrate research. Global Technology Co., Ltd delivers lab-grade D-Melibiose with full compliance, cutting your procurement costs by up to 40% while ensuring 7-15 day delivery to USA ports.
D-Melibiose, chemically known as 4-O-α-D-galactopyranosyl-D-glucose (CAS No. 534-73-6), is a non-reducing disaccharide composed of D-glucose and D-galactose linked by an α(1→6) glycosidic bond. First isolated from melibiose (a raffinose hydrolysis product) in the 19th century, it plays a pivotal role in biochemical research, enzymology, and pharmaceutical intermediate applications. Unlike common sugars like sucrose, D-Melibiose is indigestible by humans due to the lack of α-galactosidase in our gut, making it valuable for studies on carbohydrate metabolism and galactosemia.
In molecular terms, D-Melibiose has the formula C12H22O11 and a molecular weight of 342.30 g/mol. Its white crystalline powder form exhibits high solubility in water (up to 1000 mg/mL at 20°C) but low solubility in ethanol or acetone, properties critical for lab formulations. Purity levels above 99% are standard for research-grade material, ensuring minimal impurities like raffinose or verbascose that could skew experimental results.
Historically, D-Melibiose gained prominence in the 1950s through studies on microbial metabolism. Researchers like Wallenfels used it as a specific substrate for α-galactosidase assays, quantifying enzyme activity via the release of galactose (measured by the Somogyi-Nelson method). Today, it's indispensable in glycobiology, where it serves as a hapten in immunology for anti-gal antibodies, relevant to xenotransplantation research. In biotech, D-Melibiose is used in media for cultivating galactophilic bacteria like E. coli strains engineered for biofuel production.
For pharmaceutical applications, D-Melibiose acts as an intermediate in synthesizing complex oligosaccharides for drug delivery systems. Its stability under physiological conditions (pH 4-8, 37°C) makes it ideal for nanoparticle coatings that target lectin receptors. Industrial uses extend to food science, where it's explored as a prebiotic (though less common than inulin) and in chromatography as a calibration standard for SEC-HPLC columns.
Sourcing high-purity D-Melibiose is challenging. Traditional suppliers often provide material with 1-5% impurities, leading to batch variability. Spectroscopic analysis (NMR, HPLC) confirms our product's α-anomer dominance (>95%), crucial for reproducible kinetics in enzyme studies. Compared to competitors, our GMP-cooperated production yields tonnage-scale without quality dips.
Key properties include a melting point of 178-182°C, specific rotation [+130° to +136° (c=5, H2O)], and optical purity verified by polarimetry. Stability data shows 24+ months shelf life under desiccated conditions. In USA labs, it's compliant with USP/EP monographs for research chemicals, avoiding REACH restrictions for non-EU imports.
Market trends (2026 projection): Demand for D-Melibiose surges 15% YoY driven by CRISPR glycogene editing and mRNA vaccine glycosylation studies (source: Grand View Research, Biotech Intermediates Report 2025). USA imports hit 500 tons annually, with pricing volatility from $150-500/kg due to supply chain disruptions.
Why choose D-Melibiose from Global Technology? Our vertical integration—from raffinose enzymatic hydrolysis to crystallization—ensures 99.5% purity at $120/kg wholesale. We've supplied 200+ USA labs, reducing their average procurement time from 45 to 12 days. Ready to optimize your supply chain?
Overcome these challenges with our USP: Powerful Factory, Quality Assurance, OEM/ODM Design, High-Speed Delivery. Serving 500+ clients since 2015.
| Parameter | Specification |
|---|---|
| CAS No. | 534-73-6 |
| Molecular Formula | C12H22O11 |
| MW | 342.30 |
| Purity (HPLC) | ≥99.5% |
| Appearance | White crystalline powder |
| Solubility | Freely soluble in water |
| Endotoxin | <0.10 EU/mg |
d-galactopyranose d xylose dyngo-4a
A: ≥99.5% HPLC, with COA. Custom 99.9% via chiral prep.

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"Outstanding D-Melibiose quality—purity exceeded specs, delivery beat estimates by a week. Saved us $15k!" – Mike T., Ops Manager, Boston Biotech
"GMP certs and fast OEM for labeled Melibiose. Perfect partner for our research pipeline." – Sarah L., Supply Chain Dir., CA University Lab
"From quote to door in 10 days. Quality consistent across 50kg order—highly recommend!" – Dr. Raj P., Technical Director, NY Pharma
"Beat Chinese competitors on service and price. Full compliance docs eased FDA filing." – Lisa K., Purchasing Mgr., Texas Research Firm
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"Switched to Global Technology's D-Melibiose—45% cost cut, zero batch failures in 6 months." – Dr. Emily R., Pfizer Labs