D-Xylose, also known as D-xylo-pentose (CAS: 58-86-6), is a naturally occurring aldopentose sugar derived from plant hemicellulose. In the pharmaceutical, nutraceutical, and food industries, D-Xylose serves as a critical intermediate for diagnostics, sweeteners, and biofuel production. Unlike glucose, D-Xylose is not metabolized by humans, making it ideal for the D-Xylose absorption test to diagnose malabsorption syndromes like celiac disease or small intestinal bacterial overgrowth (SIBO). Administered orally at 25g doses, it measures urinary or blood excretion rates, with normal absorption exceeding 20% in 5 hours.

Chemically, D-Xylose has the molecular formula C5H10O5 and a molecular weight of 150.13 g/mol. It appears as a white crystalline powder with high solubility in water (up to 100g/100ml at 20°C) but low solubility in ethanol. Our pharmaceutical-grade D-Xylose boasts 99.5%+ purity, verified by HPLC and optical rotation [+18.8° to +20.0° (c=10, H2O)]. This surpasses USP/EP standards, ensuring batch-to-batch consistency for your formulations.

In pharmaceuticals, D-Xylose is pivotal for producing xylitol—a zero-calorie sweetener used in diabetic products and oral care (e.g., chewing gums reducing caries by 30-60% per WHO studies). It's also a precursor in microbial fermentation for ethanol and xylitol at industrial scales. Nutraceutical applications include gut health supplements, where D-Xylose probes intestinal permeability without caloric impact. By 2026, global demand for D-Xylose is projected to hit 50,000 tons annually (MarketsandMarkets report), driven by biofuel mandates in the USA and EU.

Sourcing high-purity D-Xylose wholesale is challenging amid volatile corn cob prices (primary source via acid hydrolysis). Traditional suppliers face contamination risks from heavy metals (<10ppm in our product) and microbial limits (total plate count <1000 CFU/g). Our vertically integrated process—from enzymatic hydrolysis of corncobs to spray-drying—eliminates these, yielding D-Xylose compliant with FDA 21 CFR, USP-NF, and JP monographs.

For USA importers, D-Xylose falls under HTS code 2940.00.6000, with duties averaging 6.5%. We handle FDA prior notice via our registered facility (FDA# 18536345678), ensuring seamless CBP clearance at ports like LA/Long Beach. Packaging options include 25kg fiber drums with PE liners, preserving stability (shelf life 3 years at 25°C).

LSI applications of D-Xylose extend to biotech: as a carbon source in E. coli fermentations for recombinant proteins, or in media for yeast strain engineering. In cosmetics, it's a humectant rivaling glycerin. Technical buyers appreciate our D-Xylose variants: alpha-D-Xylose hydrate, beta anomers, or 13C-labeled for NMR research. OEM/ODM services allow custom particle sizes (80-120 mesh) or micronized powders (<10μm D50) for injectables.

Market data underscores urgency: Q4 2025 saw D-Xylose spot prices spike 25% to $8-12/kg due to supply chain disruptions in Brazil/India. Our long-term contracts lock in $5.5-7.5/kg FOB Qingdao, with MOQ 100kg. Compare: European suppliers charge 40% more without GMP equivalence.

Safety profile: LD50 >30g/kg (rat, oral); non-GMO, allergen-free, Kosher/Halal certified. Regulatory filings cite D-Xylose as GRAS (FDA) for food use up to 10% in products. Environmental edge: our process recycles 95% wastewater, aligning with 2026 ESG mandates for corporate buyers.

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