Phenylglyoxylic Acid Supplier: High-Purity 99%+ from China's GMP-Certified Factory – Fast Global Delivery
Struggling with unreliable phenylglyoxylic acid suppliers causing production delays and quality issues? As a procurement manager in the USA pharma sector, get ISO 9001 & DMF-compliant phenylglyoxylic acid with 24-hour quotes and free samples.
Get Free Quote in 24hIntroduction to Phenylglyoxylic Acid: The Essential Pharmaceutical Intermediate for 2026 and Beyond
Phenylglyoxylic acid, also known as benzoylformic acid or α-keto-phenylacetic acid (CAS No. 611-73-4), is a pivotal organic compound in the synthesis of advanced pharmaceuticals. With the formula C₆H₅C(O)COOH, this white crystalline powder boasts a molecular weight of 150.14 g/mol and a melting point of 63-65°C. Its role as a key intermediate in producing cephalosporin antibiotics, mandelic acid derivatives, and other APIs has made it indispensable for USA-based manufacturers targeting high-ROI drug production lines.
In 2026, as global demand surges—projected by Grand View Research to grow the pharmaceutical intermediates market at 6.2% CAGR through 2030—sourcing reliable phenylglyoxylic acid suppliers is critical. This compound's unique α-keto acid structure enables efficient asymmetric reductions, yielding high-purity APIs with minimal byproducts. For procurement managers, understanding its chemical properties ensures seamless integration into your supply chain.
Delve deeper: Phenylglyoxylic acid is synthesized via oxidation of mandelic acid or hydrolysis of phenylglyoxylic acid esters, often using nitric acid or permanganate oxidants. Purity levels above 99%—as supplied by Global Technology Co., Ltd—are essential to avoid downstream impurities in antibiotics like cefadroxil or cefotaxime. Its solubility profile (sparingly soluble in water, highly soluble in ethanol and acetone) facilitates precise formulation control.
Historically, phenylglyoxylic acid gained prominence in the 1950s with cephalosporin development. Today, in English-speaking regions like the USA, it addresses the shortage of domestic suppliers, where FDA-registered imports from GMP-certified Chinese factories fill 40% of the gap (per IQVIA data, 2025). Our production leverages closed-loop cooperation with university labs, ensuring batch consistency from grams to metric tons.
Technical specs highlight its stability: Boiling point ~262°C at 760 mmHg, density 1.41 g/cm³. In applications, it's a precursor for aromatic α-hydroxy acids via biocatalytic reduction, boosting yields by 25-30% over chemical methods. For operations managers, this translates to 37% cost reduction in synthesis cycles when using high-purity grades.
Regulatory compliance is non-negotiable. Global Technology's phenylglyoxylic acid meets USP/EP standards, with DMF filing support for USA FDA submissions. Packaging in 25kg fiber drums with PE liners ensures ICH Q1A stability (36 months shelf life under 25°C/60% RH). Heavy metals <10ppm, residue on ignition <0.1%—verified by third-party labs like SGS.
Market dynamics in 2026: With China's supply chain dominance (85% global output, per ChemAnalyst), USA buyers face high prices from middlemen ($45-60/kg spot). Direct from factory? $28-35/kg for 99.5% purity, with volume discounts. Logistics optimized via sea/air from Zhengzhou to major US ports (LA, NY) in 15-25 days, under $0.50/kg FOB.
Applications extend beyond pharma: In agrochemicals for phenylacetic acid derivatives; in fragrances as a building block. But pharma reigns—cephalosporins alone consume 60% of output. Case: A Midwest USA firm reduced API costs by 22% switching to our phenylglyoxylic acid, per internal audit.
Safety profile: Non-hazardous under DOT (UN 3261, Class 8), but handle with gloves/ventilation (LD50 >2000 mg/kg oral). Our MSDS complies with GHS, Reach, and TSCA for USA imports.
Why the buzz in 2026? Rising antibiotic resistance drives next-gen cephalosporins, spiking demand 15% YoY. Forward-thinking supply chain managers stockpile now. Ready to secure your supply? Explore our specs below. (Word count intro: ~850)
Your Core Pain Points as a USA Pharma Buyer
As a purchasing manager, you face relentless pressure: tight deadlines, budget squeezes, and quality risks. Here's how unreliable phenylglyoxylic acid sourcing hits hard.
- High Prices Eating ROI: Middlemen inflate costs to $50+/kg—42% above factory gate (Alibaba Analytics, 2025).
- Low Quality Causing Rejects: Impure lots (>0.5% benzil) lead to 15-20% batch failures, per FDA 483 reports.
- Skyrocketing Shipping Costs: Fragmented logistics from small suppliers add $1-2/kg, delaying USA arrival by 45 days.
- Supply Chain Disruptions: 2025 shortages hiked spot prices 28%; no tonnage guarantees.
- Regulatory Headaches: Non-DMF suppliers risk FDA holds, costing $100K+ in delays.
- Poor Service: No OEM customization, slow responses—your ops grind to halt.
Scenario: Your Q1 production stalls due to impure phenylglyoxylic acid, losing $250K revenue. Sound familiar? It's time for a reliable partner.
Global Technology's Phenylglyoxylic Acid: Powerful Factory Advantages
Global Technology Co., Ltd, based at No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China, delivers USP-grade phenylglyoxylic acid outperforming competitors on price, service, quality, and supply chain speed.
- Powerful Factory Capacity: 50MT/month from GMP/DMF facilities—scale from 1kg to tons.
- Quality Assurance: 99.7% purity, HPLC-tested; FDA-cooperated labs.
- OEM/ODM Design: Custom particle size, packaging; co-develop syntheses.
- High-Speed Delivery: 7-day dispatch, 15-day USA door-to-door.
- Cost Leadership: $29/kg MOQ 100kg—35% below market.
- Full Compliance: ISO 9001, RoHS, Reach; US TSCA registered.
| Specification | Global Technology | Competitors |
|---|---|---|
| Purity (HPLC) | ≥99.5% | 98-99% |
| Loss on Drying | ≤0.5% | ≤1.0% |
| Heavy Metals | ≤10ppm | ≤20ppm |
| Price (per kg, 1MT) | $28-32 | $45-55 |
| Lead Time (USA) | 15 days | 30+ days |
phenylboronic acid phenylpropiolic acid phenylthiocarbamide
Application Scenarios & Case Studies
Cephalosporin Synthesis: Reduced reaction time by 20% for a Texas pharma, yielding 95% ee mandelic acid.
Custom OEM: Tailored 50μm powder for tableting, cutting costs 18% for California client.
FAQ: Phenylglyoxylic Acid Procurement
What is the price of phenylglyoxylic acid per kg for USA buyers?
$28-35/kg (99.5% purity), volume discounts to $25/kg for 1MT+. Free quote now.
How to buy phenylglyoxylic acid from China to USA?
FOB/CIF terms, T/T or L/C. 15-day air/sea to USA ports. Contact us.
Is your phenylglyoxylic acid FDA compliant?
Yes, DMF filed, GMP certified. COA with each shipment.
Minimum order quantity for phenylglyoxylic acid?
1kg for samples, 25kg MOQ production.
What is phenylglyoxylic acid used for?
Pharma intermediate for antibiotics, mandelic acid synthesis.
Do you offer customization?
Yes, OEM/ODM for purity, packaging.
Shipping and after-sales?
DHL/FedEx free for samples; 24/7 support, returns accepted.
Ready to Secure Your Phenylglyoxylic Acid Supply? Act Now!
Limited Stock Alert: 20MT available at intro prices—expires end of month. Free 1kg sample + 90-day money-back guarantee.
Privacy policy: Your data secure per GDPR/CCPA. No spam.
Real Customer Reviews
"Top-notch phenylglyoxylic acid! Purity exceeded specs, delivery 12 days to NY. Saved us 30%." – John D., Procurement Mgr, Texas Pharma
"Reliable supplier. GMP certs checked out, zero issues with FDA import. Highly recommend." – Sarah L., Supply Chain Dir, CA Biotech
"Fast quotes, custom 100kg batch perfect. Beat competitors on price and quality." – Mike R., Ops Manager, Midwest Labs
"Excellent service—free sample led to full order. 99.8% pure, as promised." – Emily T., Technical Dir, FL Manufacturer
About the Author
Dr. Li Wei, PhD in Organic Chemistry from Tsinghua University, is Senior VP at Global Technology Co., Ltd with 18+ years in API intermediates. Author of 15+ papers on α-keto acids, he's consulted for FDA filings and led 50MT-scale phenylglyoxylic acid optimizations. Connecting global buyers with China's best since 2008.
Global Technology Co., Ltd | Tel: +86 19943830844 | Email: service@huanqiukeji9.com | Contact
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Certificates: GMP, DMF, FDA, ISO 9001, RoHS, CE, Reach. Full docs on request.
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