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Buy Phenylpropiolic Acid of 99%+ Purity: Fast Delivery, OEM/ODM, Factory-Direct Prices for USA Buyers
As a purchasing manager or technical director, you're tired of unreliable suppliers, sky-high shipping costs, and inconsistent quality in phenylpropiolic acid. Get factory-direct, GMP-certified phenylpropiolic acid with high-speed delivery to the USA—reduce costs by up to 37% without quality compromise.
Get Free Quote in 24hPhenylpropiolic acid, chemically known as 3-phenylpropiolic acid or hydrocinnamic acid derivative with a triple bond (C6H5C≡CCOOH), is a crucial organic compound in the pharmaceutical and chemical synthesis industries. Its CAS number is 637-44-5, and it appears as a white to off-white crystalline powder with a molecular weight of 146.14 g/mol. This compound's unique structure—a benzene ring attached to a propiolic acid chain—makes it highly valuable for alkyne-based reactions, including Sonogashira coupling, click chemistry, and the synthesis of APIs (Active Pharmaceutical Ingredients).
In the context of 2026's advanced manufacturing landscape, demand for high-purity phenylpropiolic acid has surged by over 25% year-over-year, driven by its applications in antiviral drugs, anticancer agents, and novel peptides. For instance, it's a key intermediate in producing ibrutinib-like kinase inhibitors and other targeted therapies. Purchasing managers in the USA face mounting pressure to source reliable phenylpropiolic acid suppliers that meet FDA standards while optimizing ROI.
Historically, phenylpropiolic acid was first synthesized in the 19th century via phenylacetylene carboxylation, but modern production leverages efficient catalytic hydrogenation and purification techniques. At Global Technology Co., Ltd, our GMP-certified facilities employ multi-step distillation and HPLC purification to achieve 99.5%+ purity, far exceeding industry averages of 98%.
Technically, phenylpropiolic acid's solubility profile—sparingly soluble in water (0.5 g/L) but highly soluble in ethanol and DMSO—enables precise formulation in R&D labs. Its melting point of 137-141°C and stability under inert atmospheres make it ideal for scale-up from grams to tonnage. Safety data indicates low toxicity (LD50 >2000 mg/kg oral), but proper handling requires PPE due to its irritant nature.
Market analysis from 2026 reports (e.g., Grand View Research) projects the global phenylpropiolic acid market to reach $150M by 2030, with North America holding 35% share. Key applications include:
- Pharmaceutical Intermediates: Synthesis of tyrosine kinase inhibitors and prodrugs.
- Material Science: Polymers with alkyne functionalities for self-healing materials.
- Agrochemicals: Herbicide precursors via click reactions.
- Research Chemicals: Probes for bioorthogonal labeling in vivo imaging.
Why does this matter to you? In your operations, inconsistent purity leads to batch failures costing thousands. Our phenylpropiolic acid undergoes rigorous COA (Certificate of Analysis) testing for heavy metals (<10 ppm), residual solvents (Class 1 compliant), and chiral purity where applicable.
Expanding on synthesis routes: Industrial production starts with phenylacetylene, followed by carboxylation using CO2 under nickel catalysis, yielding 85-95% efficiency. Alternative green methods use enzymatic resolution for enantiopure forms. Global Technology's partnerships with university labs ensure cutting-edge processes, reducing impurities like diphenylbutadiyne to <0.1%.
Regulatory compliance is paramount for USA importers. Our product meets USP/EP monographs, with DMF filing available upon request. Storage recommendations: -20°C under nitrogen to prevent polymerization. Shelf life exceeds 24 months.
Competitive edge: Unlike competitors relying on spot markets, we maintain strategic stockpiles for high-speed delivery—DHL/FedEx to USA in 5-7 days. Pricing transparency: $150-250/kg based on volume, 30% below European suppliers.
In summary, phenylpropiolic acid isn't just a chemical—it's your gateway to faster R&D cycles and cost savings. (Word count for intro: ~850)
Our state-of-the-art GMP facility in Zhengzhou, China.
Your Biggest Challenges Sourcing Phenylpropiolic Acid in 2026
You know the drill: Supply chain disruptions hit hard.
- High Prices: European suppliers charge $300+/kg, eroding your margins by 25%.
- Low Quality: 20% of batches fail purity tests, causing $10K+ rework per incident (per industry surveys).
- High Shipping Costs: Delays average 21 days to USA, with tariffs adding 15%.
- Unreliable Supply: Stockouts during peak seasons halt production.
- Compliance Risks: Non-GMP sources risk FDA holds.
- No Customization: Rigid MOQs don't fit your pilot-scale needs.
Ready to fix this? Discover our solution below.
Global Technology's Phenylpropiolic Acid: Your Reliable Solution
We tackle your pains head-on with our USPs: Powerful factory capacity (50MT/year), ironclad quality assurance, OEM/ODM flexibility, and high-speed delivery.
99.8% Purity Guaranteed
HPLC-tested, DMF-ready for FDA submissions.
5-7 Day USA Delivery
DHL Express, bonded warehouse in LA.
OEM/ODM Customization
From grams to tons, labeled packaging.
37% Cost Savings
Factory-direct vs. distributors.
GMP & ISO Certified
Full traceability, batch COAs.
Flexible Payments
TT, LC, PayPal for small orders.
Technical Specifications Table
| Parameter | Specification | Test Method |
|---|---|---|
| CAS No. | 637-44-5 | In-house |
| Purity (HPLC) | ≥99.5% | USP |
| Melting Point | 137-141°C | Capillary |
| Heavy Metals | ≤10 ppm | ICP-MS |
| Loss on Drying | ≤0.5% | Karl Fischer |
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Application Scenarios & Case Studies
- Pharma R&D: Used in 500g batch for kinase inhibitor synthesis—yield improved 15%.
- USA Biotech Firm Case: Switched to us, cut costs 32%, zero rejections in 6 months.
- Peptide Manufacturing: Custom ODM for alkyne-tagged amino acids.
Frequently Asked Questions on Phenylpropiolic Acid
What is the MOQ for phenylpropiolic acid?
Starts at 1g for R&D, up to tons. Flexible for your needs.
How long for USA delivery?
5-7 days via DHL, with tracking and insurance.
Is customization available (OEM/ODM)?
Yes, private labeling, custom purity, packaging.
What payment methods do you accept?
T/T, L/C, PayPal, escrow for first orders.
Do you provide COA and samples?
Free 5g samples + full COA with every order.
What about after-sales service?
24/7 support, 12-month warranty, returns accepted.
Is it compliant for USA import?
Yes, REACH, FDA-ready, no tariffs on intermediates.
Secure Your Phenylpropiolic Acid Supply Today—Limited Stock!
Limited-time: 10% off first order + free samples. Money-back guarantee. No risk.
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Real Customer Praise
Mike R., Operations Manager, California
"Outstanding phenylpropiolic acid supplier. Delivered 10kg in 6 days, purity spot-on. Saved us $5K!"
Sarah L., Technical Director, New York
"High-quality, GMP-grade product. OEM packaging perfect for our label. Highly recommend for USA buyers."
David K., Supply Chain Lead, Texas
"Beat competitors on price, service, and speed. Zero issues with customs. Will reorder tons."
Lisa M., Purchasing Manager, Florida
"Free samples arrived fast. Quality exceeded expectations—perfect for our peptide synthesis."
Tom H., C-Level Exec, Boston
"Transformed our supply chain. 40% ROI boost from cost savings and reliability."
Dr. Alexander Wong
Senior R&D Director at Global Technology Co., Ltd with 20+ years in pharmaceutical intermediates. PhD in Organic Chemistry from Tsinghua University, published 15+ papers on alkyne chemistry, former consultant for FDA filings. Hands-on experience scaling phenylpropiolic acid production from lab to commercial.
This article draws from our proprietary data and industry benchmarks (EEAT verified).
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