Name: High-Purity β-Endorphin (18-31) for Wellness | CAS 74216-35-6
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β-Endorphin (18-31) (human) CAS NO.74216-35-6

β-Endorphin (18-31) (human) is a C-terminal fragment derived from the endogenous opioid peptide β-Endorphin, specifically designed for advanced biochemical and pharmacological research. Unlike the full-length peptide, this fragment lacks the N-terminal enkephalin sequence required for classical opioid receptor binding, making it an ideal tool for investigating non-opioid signaling pathways, immune modulation, and the structural determinants of endorphin function in experimental settings.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	β-Endorphin (18-31) (human)
CAS NO.	74216-35-6
Appearance	White to off-white lyophilized powder
Molecular Formula	C₇₅H₁₂₂N₂₀O₂₀
Molecular Weight	1651.9g/mol
Purity (RP-HPLC)	≥95%
Solubility	Soluble in 1M acetic acid, DMSO, or deionized water
Endotoxin	≤1 EU/mg
Biological Activity	Modulates immune cell function and non-opioid signaling pathways
Storage Conditions	Store at -20°C, protected from light and moisture
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

This peptide operates primarily through non-opioid mechanisms, as it does not bind significantly to classical mu or delta opioid receptors due to the absence of the N-terminal tyrosine residue. Research indicates it modulates cellular functions via interactions with specific non-opioid receptors on immune cells, such as T-lymphocytes, influencing intracellular signaling cascades without triggering typical opioid-mediated analgesia or being blocked by naloxone.

2.PRODUCT INDICATIONS

This product is intended for use in scientific research focused on neuroimmunology, psychoneuroendocrinology, and the development of novel therapeutic strategies targeting non-opioid pathways. It is suitable for in vitro and in vivo experimental models studying immune response regulation, stress-induced analgesia mechanisms, and the differential roles of endorphin fragments versus full-length peptides in physiological and pathological processes.

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3.CLINICAL EFFICACY OF PRODUCT

While not intended for clinical use, β-Endorphin (18-31) (human) serves as a critical research tool for elucidating the mechanisms underlying immune modulation and non-opioid signaling. Preclinical studies utilizing this fragment have contributed to a deeper understanding of how endorphin-derived peptides can influence inflammatory responses and cellular behavior independently of traditional opioid pathways, supporting its value in advancing research for conditions involving immune dysregulation and neuroendocrine interactions.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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