2,3,4,5-Tetracaffeoyl-D-Glucaric acid (CAS NO.1419478-52-6) is a high-purity natural product derivative characterized by its dense phenolic hydroxyl groups. This sophisticated phytochemical serves as a potent reactive oxygen species (ROS) inhibitor, specifically disrupting oxidative bursts in human neutrophils and neutralizing free radicals, making it an indispensable tool for advanced biochemical research.
Engineered for precision in non-clinical applications, this compound exhibits remarkable anti-adipogenic and antioxidant properties. By modulating transcriptional regulators and suppressing lipid droplet accumulation, it provides researchers in dermatology, immunology, and metabolic studies a reliable standard for evaluating therapeutic agents against obesity and premature cellular aging.
| Product Name | 2,3,4,5-Tetracaffeoyl-D-Glucaric acid | CAS NO. | 1419478-52-6 |
|---|---|---|---|
| Molecular Formula | C42H34O20 | Molecular Weight | 858.71g/mol |
| Purity (RP-HPLC) | ≥95% | Appearance | Brown to dark brown amorphous powder |
| Solubility | Soluble in 1M acetic acid, DMSO, or deionized water | Endotoxin | < 10 EU/mg |
| Storage Condition | Store at -20°C, protected from light and moisture | MOQ | 1g |
Effectively neutralizes superoxide anions and peroxynitrite, preventing lipid peroxidation and protecting cellular DNA.
Protects human fibroblasts from cytokine-induced damage, mitigating premature skin aging in dermatological models.
Inhibits triglyceride accumulation in preadipocytes, serving as a critical tool for obesity and metabolic disorder research.
Tetra-substituted structure offers enhanced biological activity compared to simpler mono- or di-caffeoyl derivatives.
Ideal primary standard for HPLC and mass spectrometry to quantify bioactive phenolics in herbal extracts.
Produced under rigorous quality management systems with complete COA, HPLC, and MS documentation.
Rigorous quality management ensuring high-purity biotechnological products with full batch traceability.
Standardized production systems covering synthesis, purification, and testing in compliant facilities.
Secure international air freight via DHL, FedEx, and UPS for rapid, temperature-stable delivery.
Flexible packaging solutions tailored to specific research requirements to ensure product integrity.
Partnering with renowned university laboratories to provide gram-to-ton level supply capacities.
Adhering to international trade standards and FDA/DMF guidelines for pharmaceutical intermediates.
| Comparison Metric | Standard Derivatives | Tetracaffeoyl-D-Glucaric |
|---|---|---|
| Antioxidant Capacity | Moderate | Exceptional (High-Density) |
| ROS Inhibition Rate | Baseline | Significantly Enhanced |
| Anti-Adipogenic Effect | Low to Moderate | High Efficacy |
| Mitochondrial Protection | Limited | Robust Preservation |
| Analytical Precision | Variable | High-Standard Reference |
It is primarily used in non-clinical research for obesity and metabolic disorders, acting as a tool to evaluate anti-adipogenic drug candidates and study fat accumulation pathways.
Due to its tetra-substituted structure, it provides significantly more potent antioxidant and anti-adipogenic activity compared to simpler derivatives.
The product should be stored at -20°C, kept in a tightly sealed container, and protected from both light and moisture to prevent degradation.
Yes, it is an essential primary standard for phytochemists and analytical chemists to quantify bioactive phenolics in herbal extracts using HPLC and mass spectrometry.
We utilize reliable international air freight services including DHL, FedEx, UPS, and TNT to ensure speed and minimize environmental impact during transit.
Each batch comes with a complete Certificate of Analysis (COA), RP-HPLC purity report, and MS chromatograms, with third-party testing available upon request.