3′-O-Angeloylhamaudol CAS NO.84272-84-4
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | 3'-O-Angeloylhamaudol |
| CAS NO. | 84272-84-4 |
| Appearance | White to off-white powder |
| Molecular Formula | C20H22O6 |
| Molecular Weight | 358.39 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in DMSO, methanol; slightly soluble in water; insoluble in hexane |
| Endotoxin | < 0.01 EU/mg (LAL test) |
| Biological Activity | Inhibits VEGFR-2 phosphorylation; modulates intestinal intraepithelial lymphocyte activity |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The compound exerts its effects through a dual mechanism: it inhibits tumor-induced angiogenesis by blocking the phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) in endothelial cells, thereby cutting off the blood supply to tumors. Simultaneously, it activates intestinal intraepithelial lymphocytes, enhancing the body's immune surveillance and response against cancerous cells, which is particularly effective in models like colon 26-bearing mice.
2.PRODUCT INDICATIONS
3'-O-Angeloylhamaudol is indicated for research into anti-tumor and anti-inflammatory therapies. It is particularly relevant for studies focusing on colon cancer and gastric adenocarcinoma, where its ability to inhibit cell growth and modulate immune responses is most pronounced. Researchers in oncology and immunology use this compound to explore its potential in developing new treatments for solid tumors and inflammatory conditions.
3.CLINICAL EFFICACY OF PRODUCT
In preclinical studies, 3'-O-Angeloylhamaudol has demonstrated significant anti-tumor efficacy by effectively inhibiting tumor growth in animal models. It has shown promising results in reducing tumor size and metastasis through its anti-angiogenic properties and immune activation. While clinical data in humans is still emerging, the compound's strong performance in laboratory settings positions it as a promising candidate for further clinical development in cancer therapy.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
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1.A rigorous quality management system
2.Batch traceability and stability data
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Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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