4-hydroxybenzophenone CAS1137-42-4

4-hydroxybenzophenone CAS1137-42-4

4-hydroxybenzophenone CAS1137-42-4

4-hydroxybenzophenone CAS1137-42-4

4-hydroxybenzophenone CAS1137-42-4

4-Hydroxybenzophenone is a chemical compound commonly used as a UV filter. It helps absorb ultraviolet light, making it useful in products like sunscreens, cosmetics, and plastics to protect against sun damage. The compound is a white crystalline solid and is mostly soluble in organic solvents. It is also used in the production of other chemicals, such as UV stabilizers for various applications.

Mechanism of Action


4-Hydroxybenzophenone functions primarily as a UV absorber. Its mechanism involves the absorption of ultraviolet (UV) light, particularly in the UV-B range (280–320 nm). The compound contains a benzophenone structure, which allows it to absorb UV radiation effectively. This absorbed energy is then dissipated as heat, preventing the UV rays from damaging the molecules in products or materials. In cosmetics and sunscreen formulations, it helps protect the skin from sunburn and premature aging caused by UV exposure. Additionally, 4-hydroxybenzophenone can act as an UV stabilizer in materials like plastics and coatings, preventing the degradation of these materials due to prolonged UV exposure.

Indications


4-Hydroxybenzophenone is mainly used in the following areas:

  1. Sunscreens & Cosmetics: It is used in topical skincare products such as sunscreens, lotions, and creams to provide protection against harmful UV radiation.

  2. Plastic & Polymer Industry: It is added to plastics, coatings, and paints to protect these materials from UV-induced degradation, ensuring longevity and durability.

  3. Photoprotective Additives: It is incorporated into other formulations to prevent photo-oxidation and UV degradation of various products, such as adhesives and fabrics.


Clinical Efficacy


  • In Sunscreens: 4-Hydroxybenzophenone is effective at preventing skin damage from UV radiation by absorbing UV rays and reducing the risk of sunburn, photoaging, and DNA damage. As an active ingredient in sunscreens, it contributes to broad-spectrum UV protection, although its effectiveness may vary depending on concentration and formulation.

  • Material Protection: In materials like plastic and coatings, 4-hydroxybenzophenone is clinically effective in prolonging the life of the product by preventing UV-induced degradation, such as fading or cracking, especially in outdoor applications.




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