ACTH 1839 Human CAS 53917423 Peptide Suppliers and Factory in China
ACTH (18-39) (human), identified by CAS NO.53917-42-3, is a high-precision synthetic peptide fragment designed for advanced endocrine and pharmacological research. This potent melanocortin receptor agonist specifically targets the MC2 receptor on adrenal cortical cells, facilitating the study of cortisol biosynthesis and the modulation of the HPA axis with exceptional specificity.
By eliminating the N-terminal regions of pro-opiomelanocortin (POMC), this fragment serves as a critical tool for isolating adrenal-specific responses from pituitary or neural interference. It is an indispensable reagent for researchers investigating Addison's disease, Cushing's syndrome, and the complex mechanisms of steroidogenesis in academic and pharmaceutical biotechnology environments.
Detailed Parameters
| Product Name | ACTH (18-39) (human) | CAS NO. | 53917-42-3 |
|---|---|---|---|
| Appearance | White to off-white lyophilized powder | Molecular Formula | C₁₁₂H₁₆₅N₂₇O₃₆ |
| Molecular Weight | 2465.7 g/mol | Purity (RP-HPLC) | ≥98.0% |
| Solubility | 1M acetic acid, DMSO, or deionized water | Endotoxin | < 1 EU/mg |
| Storage Conditions | Store at -20°C, protected from light/moisture | MOQ | 1 mg |
Key Advantages
Ultra-High Purity
Achieving ≥98.0% purity via RP-HPLC to ensure consistent and reproducible experimental results.
Specific Target Action
Selective binding to MC2R, minimizing confounding effects from other pituitary pathways.
Low Endotoxin Level
Strictly controlled at < 1 EU/mg, ideal for sensitive preclinical and cellular models.
Translational Relevance
Consistent biological activity across multiple species, enhancing the validity of animal studies.
GMP-Compliant Quality
Produced under rigorous quality management systems with full batch traceability.
Comprehensive Documentation
Every batch includes COA, HPLC reports, and MS chromatograms for total transparency.
Product Gallery
Management Platforms
Quality Control
Rigorous testing using HPLC and Mass Spectrometry to verify purity and sequence.
GMP Production
Standardized synthesis and purification processes adhering to international GMP standards.
Cold Chain Logistics
Specialized temperature-controlled shipping to maintain peptide stability and integrity.
Global Distribution
Strategic stock locations in USA, Germany, and China for rapid worldwide delivery.
Batch Traceability
Complete documentation trail from raw material procurement to final packaging.
Custom Synthesis
Flexible scaling from milligram levels for research to ton-level for industrial needs.
Investment Return Comparison
| Metric | Standard Grade | Our Research Grade |
|---|---|---|
| Purity Level | ≥95% | ≥98% (Verified) |
| Endotoxin Control | Unspecified | < 1 EU/mg |
| Documentation | Basic COA | COA + HPLC + MS |
| Delivery Speed | Standard Freight | Priority Air (DHL/FedEx) |
| Stability Data | Limited | Comprehensive Batch Data |
Frequently Asked Questions
It is primarily used in academic and pharmaceutical research to study adrenal physiology, cortisol release, and the treatment of endocrine disorders like Addison's disease.
The product should be stored at -20°C and kept strictly protected from light and moisture to prevent degradation.
Yes, it is soluble in deionized water, as well as 1M acetic acid and DMSO, depending on your specific experimental requirements.
Our production partners employ GMP-compliant systems and hold various certifications including DMF and FDA to ensure global pharmaceutical standards.
Yes, third-party testing reports are available upon request to supplement our internal HPLC and MS data.
We utilize international air freight via DHL, FedEx, UPS, and TNT to ensure the fastest transit times and maintain cold chain integrity.
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