AICAR
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | AICAR (Acadesine) |
| CAS NO. | 2627-69-2 |
| Appearance | Off-white to light brown powder |
| Molecular Formula | C₉H₁₄N₄O₅ |
| Molecular Weight | 258.2 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in DMSO (> 50 mg/mL) and water (~20 mg/mL); insoluble in non-polar solvents |
| Endotoxin | ≤ 0.1 EU/mg (for research-grade ) |
| Biological Activity | Potent AMP-activated protein kinase (AMPK) activator; stimulates glucose uptake and fatty acid oxidation; induces autophagy and metabolic regulation in vitro and in vivo |
| Storage Conditions | Lyophilized powder: Store at -20°C in a dry, dark place; stable for 24–36 months. Reconstituted solutions (DMSO or water): Store at -20°C, protected from light, and use within 1–3 months; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
AICAR is metabolized within cells to form ZMP, an analog of AMP, which directly activates AMPK by binding to its γ-regulatory subunit. This activation triggers a cascade of downstream effects, including increased glucose uptake via GLUT4 translocation, enhanced fatty acid oxidation, and inhibition of anabolic processes like gluconeogenesis and cholesterol synthesis. It also promotes mitochondrial biogenesis and autophagy, mimicking cellular adaptation to low-energy states and exercise.
2.PRODUCT INDICATIONS
This product is indicated for research in metabolism, diabetes, cardiovascular disease, and sports science. It serves as a key tool for studying insulin resistance, ischemic preconditioning, muscle fiber type switching, and non-alcoholic fatty liver disease. Researchers also utilize AICAR to explore therapeutic strategies for metabolic syndrome, aging-related energy decline, and conditions where AMPK activation may confer protective benefits.
3.CLINICAL EFFICACY OF PRODUCT
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
