Antide Acetate CAS NO.112568-12-4

Antide Acetate CAS NO.112568-12-4

Antide Acetate CAS NO.112568-12-4

Antide Acetate CAS NO.112568-12-4

Antide Acetate CAS NO.112568-12-4

Antide Acetate (CAS NO. 112568-12-4) is a synthetic, decapeptide antagonist of Gonadotropin-Releasing Hormone (GnRH). It is a potent, long-acting inhibitor designed to block the action of endogenous GnRH at its pituitary receptor. This high-purity, acetate salt form is supplied as a lyophilized powder for research applications. It is widely used in reproductive endocrinology, oncology, and veterinary science to study and suppress the hypothalamic-pituitary-gonadal (HPG) axis, effectively inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Antide Acetate
CAS NO.
112568-12-4
Appearance
White to off-white lyophilized powder
Molecular Formula
C82H108N17O14C1
Molecular Weight
1591.32g/mol
Amino Acid Sequence
Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-N-MeTyr-D-Asn-Leu-Lys(iPr)-Pro-D-Ala-NH₂ (cyclic decapeptide, N-terminal acetylated)
Purity (RP-HPLC)
≥98.0%
Solubility
Soluble in water, ethanol, DMSO, and acetic acid solution
Endotoxin
< 1.0 EU/mg
Biological Activity
Potent gonadotropin-releasing hormone (GnRH) antagonist; suppresses LH and FSH release, used in research on hormone-dependent cancers and reproductive disorders.
Storage Conditions

Store at –20°C, protected from light and moisture.

Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Antide Acetate acts as a potent competitive antagonist of the gonadotropin-releasing hormone receptor (GnRHR). By binding to these receptors in the pituitary gland, it inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing gonadal steroidogenesis and reducing circulating levels of sex hormones like testosterone and estrogen.

2.PRODUCT INDICATIONS

This product is primarily used in research settings for studying hormone-dependent conditions, such as prostate cancer, breast cancer, endometriosis, and uterine fibroids. It is also applied in reproductive biology research, including studies on fertility regulation and the development of novel hormonal therapies.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical and clinical studies have demonstrated that Antide Acetate effectively suppresses gonadotropin and sex steroid levels, leading to the inhibition of tumor growth in hormone-sensitive cancers and the alleviation of symptoms in sex hormone-dependent disorders. Its efficacy in achieving medical castration and managing endocrine-related pathologies supports its investigational use in therapeutic development.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.


5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


 We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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If you have any product requirements, please send an email to:business@huanqiukeji9.com

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