ARA290 (Cibinetide) CAS NO.1208243-50-8

ARA290 (Cibinetide) CAS NO.1208243-50-8

ARA290 (Cibinetide) CAS NO.1208243-50-8

ARA290 (Cibinetide) CAS NO.1208243-50-8

ARA290 (Cibinetide) CAS NO.1208243-50-8

ARA290 (Cibinetide) is a groundbreaking 11-amino acid synthetic peptide derived from the tissue-protective domain of erythropoietin (EPO), engineered to provide potent anti-inflammatory and neuroprotective benefits without stimulating red blood cell production. This non-erythropoietic peptide is a premier research tool for studying nerve regeneration and chronic inflammatory conditions, offering a unique mechanism focused on cellular repair rather than hematopoiesis.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
ARA290 (Cibinetide)
CAS NO.
1208243-50-8
Appearance
White to off-white crystalline powder
Molecular Formula
C₅₁H₈₄N₁₆O₂₁
Molecular Weight
1257.31 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility

Soluble in water; partially soluble in acidic aqueous solutions; insoluble in organic solvents like ethanol or DMSO at room temperature

Endotoxin< 0.5 EU/mg (for pharmaceutical-grade material)
Biological Activity
Potent erythropoietin receptor agonist with selective activity in the brain, heart, and spinal cord; promotes neuroprotection, tissue repair, and anti-inflammatory responses without erythropoietic effects
Storage Conditions
Store at 2–8°C in a dry, dark place; protect from light and moisture
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Cibinetide selectively binds to and activates the Innate Repair Receptor (IRR), a heterodimeric complex of the EPO receptor and the β-common receptor (CD131). This targeted activation triggers downstream signaling pathways that inhibit apoptosis, reduce pro-inflammatory cytokine production (such as TNF-α and IL-6), and promote axonal sprouting, thereby facilitating tissue repair and nerve regeneration without affecting erythropoiesis or blood viscosity.

upload/attachment/image/202603/26/17745015186ea076052e4d9836cac0939b1ddf834d_local.pngupload/attachment/image/202603/26/177450152389a84fa177e06b686033882d528efc1f_local.png

2.PRODUCT INDICATIONS

This product is indicated for preclinical research into small fiber neuropathy (SFN), diabetic peripheral neuropathy, and sarcoidosis-associated nerve damage, focusing on pain relief and nerve fiber density restoration. It is also utilized in studies of metabolic syndrome, ischemic tissue injury, and autoimmune conditions where tissue protection and anti-inflammatory modulation are key therapeutic goals.

upload/attachment/image/202603/26/1774501530ffe95275f1dd3ddad942e8e9459782a9_local.png

3.CLINICAL EFFICACY OF PRODUCT

In Phase 2 clinical trials, ARA290 demonstrated significant efficacy in improving neuropathic pain scores and increasing corneal nerve fiber density in patients with sarcoidosis and diabetic neuropathy. Studies also report enhanced metabolic control and improved exercise capacity, with a favorable safety profile and no serious adverse events related to hematocrit elevation.

upload/attachment/image/202603/26/17745015362674cc6657fe128b54b57e88e52f0045_local.png

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

upload/attachment/image/202603/11/1773189972ab0555af1b2c5503d2db96642a80e122_local.png

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

upload/attachment/image/202601/20/1768872924be74a0641f7ddbf20e541c97f2066c5c_local.jpg


Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags: ARA290 #Cibinetide #Neuropathy #NerveRegeneration #InnateRepairReceptor #AntiInflammatory #ResearchPeptide #TissueProtection


If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157

Premium API Oxandrolone Ucinky Manufacturing
May 25, 26
Premium API Oxandrolone Ucinky Manufacturing
Premium API Oxandrolone Ucinky Manufacturing Leading global supplier of high-purity chemical raw materials for pharmaceutical grade Oxandrolone Ucinky, combining precision engineering with industrial scale. 5000 kg Annual Output 120 Countries Served 5 Days Sample Lead Time 99.7 On-Time Delivery Industrial Precision Pure Chemical Synthesis Engineering the future of pharmaceutical intermediates with unmatched stability. Our facility stands as a global leader in the oxandrolone ucinky sector, utilizing CRYOGENIC CRYSTALLIZATION and advanced chromatography to ensure an assay purity exceeding 99.8. We integrate a fully automated closed-loop system that eliminates human error and contamination.
Clinical Benefits and Applications of Oxandrolone Therapy
May 22, 26
Clinical Benefits and Applications of Oxandrolone Therapy
Oxandrolone therapy represents a sophisticated intersection of endocrine science and regenerative medicine, primarily utilized to address muscle wasting and metabolic dysfunction. In the global pharmaceutical landscape, this specific approach to androgen therapy is valued for its unique ability to promote protein synthesis while exhibiting a lower androgenic profile compared to traditional steroids, making it a critical tool for patients recovering from severe trauma or chronic illness. From a clinical perspective, understanding the nuances of oxandrolone therapy is essential for optimizing patient outcomes in weight gain and tissue repair.
Clinical Benefits and Production of Oxandrolone Steroid
May 20, 26
Clinical Benefits and Production of Oxandrolone Steroid
The global pharmaceutical landscape has seen a significant rise in the demand for highly specialized anabolic agents, among which the oxandrolone steroid stands out due to its unique chemical profile and therapeutic versatility. As a modified version of dihydrotestosterone, this compound provides a potent means of addressing muscle wasting and metabolic deficits, making it a critical asset in both clinical rehabilitation and advanced physiological research. Understanding the nuances of this synthetic compound is essential for healthcare providers and researchers alike, as it balances efficacy with a relatively lower androgenic profile compared to other steroids.

If you are interested in our products, you can choose to leave your information here, and we will be in touch with you shortly.