Astragalin CAS NO.480-10-4
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Astragalin |
| CAS NO. | 480-10-4 |
| Appearance | Fine off-white to light yellow powder |
| Molecular Formula | C21H20O11 |
| Molecular Weight | 448.38 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in DMSO, methanol, ethanol; sparingly soluble in water |
| Endotoxin | <0.01 EU/mg (LAL test) |
| Biological Activity | Potent antioxidant, anti-inflammatory, anti-cancer, neuroprotective activity |
| Storage Conditions | Store at -20°C in a dry, dark place; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Astragalin exerts its effects primarily by modulating key signaling pathways. It inhibits the activation of NF-κB and MAPK pathways, which are central to inflammatory responses, thereby reducing the production of inflammatory mediators like NO and PGE2. Additionally, it activates autophagy and inhibits apoptosis in cells, particularly in neurodegenerative models, by regulating pathways such as PI3K/Akt/mTOR and Fas/FasL-VDAC1, contributing to its neuroprotective and anti-cancer activities.
2.PRODUCT INDICATIONS
This product is indicated for research and development in areas such as anti-inflammatory therapies, neuroprotection, and oncology. It is particularly relevant for studies involving osteoarthritis, Alzheimer's disease, and various cancers, including breast and colon cancer. Researchers focusing on natural product pharmacology, drug discovery, and functional food development will find this compound applicable for investigating its therapeutic potential against chronic inflammatory and degenerative diseases.
3.CLINICAL EFFICACY OF PRODUCT
Clinical and preclinical studies have demonstrated that Astragalin effectively alleviates inflammatory pain, improves cognitive function in neurodegenerative models, and inhibits tumor growth and metastasis. It has shown efficacy in reducing bone destruction in cancer metastasis models and ameliorating symptoms in experimental colitis and arthritis. These findings support its potential as a therapeutic agent for managing inflammation-related disorders and certain types of cancer.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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