Baicalein CAS NO.491-67-8

Baicalein CAS NO.491-67-8

Baicalein CAS NO.491-67-8
Baicalein CAS NO.491-67-8
Baicalein CAS NO.491-67-8

Baicalein CAS NO.491-67-8

Baicalein CAS NO.491-67-8

Baicalein (CAS No. 491-67-8) is a high-purity flavonoid compound with the molecular formula C₁₅H₁₀O₅ and a molecular weight of 270.24 g/mol. Derived from the roots of Scutellaria baicalensis, it is widely studied for its diverse biological activities and applications in pharmaceutical, nutraceutical, and cosmetic research.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Baicalein
CAS NO.
491-67-8
Appearance
Bright yellow to yellow crystalline powder
Molecular Formula
C₁₅H₁₀O₅
Molecular Weight
270.24 g/mol
Amino Acid SequenceNot applicable (flavonoid compound)
Purity (RP-HPLC)
≥98.0%
Solubility

Soluble in DMSO, ethanol, and methanol; slightly soluble in water; insoluble in nonpolar organic solvents

Endotoxin<0.1 EU/mg
Biological Activity
Natural flavonoid with anti-inflammatory, antioxidant, antiviral, and anticancer properties; widely studied in pharmacological and nutraceutical research.
Storage Conditions
Store at 2–8°C, protected from light and moisture.
Stock Location
Stock in USA
MOQ
100mg


1.MECHANISM OF ACTION

Baicalein exerts its effects primarily through potent antioxidant and anti-inflammatory pathways. It functions by scavenging free radicals, modulating key signaling molecules such as NF-κB and MAPK, and inhibiting enzymes like cyclooxygenase and lipoxygenase, thereby reducing oxidative stress and inflammatory responses at the cellular level.


2.PRODUCT INDICATIONS

This natural compound is investigated for use in anti-inflammatory formulations, neuroprotective supplements, skincare products targeting oxidative damage, and as a complementary agent in metabolic and cardiovascular health research. It is also applied in studies related to liver protection, antiviral activity, and cancer chemoprevention.


3.CLINICAL EFFICACY OF PRODUCT

Clinical and preclinical studies have demonstrated Baicalein’s ability to improve markers of inflammation, enhance antioxidant status, and support cellular health. Research indicates potential benefits in managing inflammatory conditions, protecting neuronal function, and contributing to skin vitality, though further human trials are ongoing to confirm its therapeutic efficacy.


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