Name: Boc-D-Tyr(tBu)-OH CAS 67342-89-2 High-Purity Amino Acid
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Boc-D-Tyr(tBu)-OH CAS NO. 67342-89-2

Boc-D-Tyr(tBu)-OH is a protected D-amino acid building block for peptide synthesis. Its Boc and tBu groups enable controlled coupling, while the D-tyrosine core dramatically enhances peptide metabolic stability. It is essential for developing long-acting peptide therapeutics and stabilized biomaterials, serving the biopharmaceutical R&D and CDMO industries.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Boc-D-Tyr(tBu)-OH
CAS NO.	67342-89-2
Appearance	White to off-white crystalline powder
Molecular Formula	C₂₀H₂₉NO₅
Molecular Weight	363.45 g/mol
Purity (RP-HPLC)	≥95%
Solubility	Soluble in common organic solvents (dichloromethane, methanol, ethanol, DMSO, DMF); sparingly soluble in water
Endotoxin	< 1.0 EU/mg
Biological Activity	This product is a protected amino acid derivative, serving as a critical building block in solid-phase peptide synthesis (SPPS).
Storage Conditions	Store at 2–8°C in a cool, dry environment, protected from light and moisture. For long-term stability
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

As a protected amino acid derivative, Boc-D-Tyr(tBu)-OH serves as a specialized synthetic intermediate rather than possessing direct biological activity. Its chemical mechanism involves sequential deprotection during peptide synthesis: The Boc group is selectively removed under acidic conditions (typically TFA or HCl in organic solvents) to expose the α-amino group for peptide coupling, while the tBu protection on the phenolic hydroxyl remains intact.

2.PRODUCT INDICATIONS

Therapeutic Peptide Synthesis – Essential for incorporating D-tyrosine in peptide drugs requiring enhanced stability.

Enzyme Inhibitor Development – Building block for tyrosine-containing protease and kinase inhibitors.

Radiopharmaceuticals – Intermediate for tyrosine-based radiolabeled compounds and imaging agents.

Neuropeptide Research – Used in synthesizing D-amino acid containing neuroactive peptides.

Structural Studies – For peptides requiring specific tyrosine orientations in conformational studies.

3.CLINICAL EFFICACY OF PRODUCT

While Boc-D-Tyr(tBu)-OH itself lacks direct clinical efficacy, peptides synthesized using this building block demonstrate significant therapeutic advantages. D-Tyrosine-containing peptides exhibit enhanced resistance to proteolytic degradation, improved pharmacokinetic profiles, and prolonged biological activity compared to their L-configured counterparts.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.

Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.