Name: C20-OtBu-Glu(AEEA) Intermediate for Long-Acting Peptide Drugs
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C20-Otbu-glu-otbu CAS NO.1119061-70-9

C20-Otbu-glu-otbu (CAS No. 1119061-70-9) is a high-purity chemical intermediate designed for pharmaceutical and biochemical applications. While the molecular formula and molecular weight are proprietary and provided upon request, this lipopeptide derivative is widely used in the design of targeted drug delivery systems and peptide conjugation.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	C20-OtBu-Glu(OtBu)
CAS NO.	1119061-70-9
Appearance	White to off-white powder or solid
Molecular Formula	C₂₆H₄₇NO₅
Molecular Weight	453.7 g/mol
Amino Acid Sequence	CH₃(CH₂)₁₈CO-Glu(OtBu)-OH (C20 fatty acid chain linked to γ-tert-butyl protected glutamic acid)
Purity (RP-HPLC)	≥95%
Solubility	Soluble in DMF, DMSO, and dichloromethane; slightly soluble in methanol; insoluble in water
Endotoxin	<1.0 EU/mg
Biological Activity	Lipopeptide intermediate used for enhancing lipophilicity, membrane permeability, and cellular uptake in peptide conjugation and prodrug design.
Storage Conditions	Store at –20°C, protected from light and moisture.
Stock Location	Stock in USA
MOQ	10mg

1.MECHANISM OF ACTION

The compound acts as a versatile linker by combining a long-chain fatty acid (C20) with a protected glutamic acid moiety, enhancing lipophilicity and facilitating membrane penetration. This structure supports the conjugation of therapeutic or diagnostic payloads, enabling improved bioavailability and targeted cellular uptake.

2.PRODUCT INDICATIONS

C20-Otbu-glu-otbu is applied in the synthesis of peptide-drug conjugates, lipid-based prodrugs, and targeted delivery platforms, particularly in oncology, vaccine development, and molecular imaging research. It serves as a key building block in formulations requiring enhanced tissue specificity and pharmacokinetic control.

3.CLINICAL EFFICACY OF PRODUCT

As a research-grade intermediate, this compound itself is not used in clinical practice. Its value lies in enabling the development of advanced therapeutic conjugates, which may later undergo preclinical and clinical evaluation for improved efficacy, reduced off-target effects, and optimized delivery in treatments such as cancer therapy or metabolic disorders.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.