Cecropin P1 (CAS NO.125667-96-1) is a high-purity antimicrobial peptide engineered for advanced laboratory research and preclinical studies. Characterized by its potent broad-spectrum activity, it specifically targets Gram-negative bacteria through a unique "carpet-like" membrane-disruption mechanism, making it an invaluable tool for researchers focusing on antimicrobial discovery, virology, and membrane biology.
Designed to overcome the limitations of traditional antibiotics, Cecropin P1 targets the fundamental integrity of the microbial envelope rather than specific intracellular enzymes. This physical mode of action significantly reduces the likelihood of microbial resistance, providing a robust framework for investigating lead compounds in drug discovery pipelines for treating bacterial sepsis and viral infections such as PRRSV.
| Product Name | Cecropin P1 | CAS NO. | 125667-96-1 |
|---|---|---|---|
| Appearance | White to off-white lyophilized powder | Molecular Formula | C147H253N45O43 |
| Molecular Weight | 3338.91 g/mol | Purity (RP-HPLC) | ≥99.0% |
| Endotoxin | ≤0.5 EU/mg | Solubility | Soluble in water, dilute acetic acid |
| Storage Condition | Store at -20°C, dry and dark | Stock Location | USA Warehouse |
Physical membrane disruption prevents classical microbial resistance seen in traditional antibiotics.
Demonstrates fast bactericidal activity at micromolar concentrations against clinically relevant pathogens.
RP-HPLC purity ≥99.0% ensures consistent and reproducible results for sensitive research assays.
Effective against Gram-negative bacteria, antiparasitic effects, and anticancer cell proliferation.
Proven ability to block viral attachment and replication, specifically targeting PRRSV.
Produced via GMP-compliant systems with full COA, MS, and HPLC documentation provided.
Rigorous tracking from raw material procurement to final packaging for every batch.
Standardized testing including MS chromatograms and third-party validation reports.
Specialized packaging to maintain -20°C stability during international transit.
Reliable shipping via DHL, FedEx, and UPS with advanced real-time tracking systems.
Capacity to supply from gram-level research kits up to ton-level industrial quantities.
Compliance with international trade standards and GMP/FDA certified partner labs.
| Feature | Standard Peptides | GlobalTech Cecropin P1 |
|---|---|---|
| Purity Level | 95% – 98% | ≥99.0% (Certified) |
| Mechanism | Enzyme Inhibitory | Membrane Disruptive |
| Resistance Risk | High Probability | Significantly Low |
| Spectrum | Narrow/Specific | Broad-Spectrum |
| Documentation | Basic COA | Full COA, HPLC & MS |
It is primarily used as a reference peptide for determining minimum inhibitory concentrations (MICs) against ESKAPE organisms and researching antimicrobial peptide structure-activity relationships.
Unlike antibiotics that target intracellular enzymes, Cecropin P1 uses a "carpet-like" mechanism to disintegrate the microbial membrane, making it harder for bacteria to develop resistance.
Yes, it is indicated for virology assays, specifically for blocking viral attachment and replication of pathogens like PRRSV.
It should be stored at -20°C in a dry, dark, and well-sealed container, avoiding repeated freeze-thaw cycles to maintain stability.
Each batch is produced in GMP-compliant systems and includes a Certificate of Analysis (COA), HPLC purity report, and mass spectrometry (MS) chromatograms.
No, this product is designated strictly for laboratory research, preclinical studies, and quality control applications; it is not approved as a clinical therapeutic agent.