Name: Conotoxin CAS NO.936616-33-0
Availability: InStock
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Conotoxin CAS NO.936616-33-0

Conotoxin (μ-Conotoxin CnIIIC) is a highly specific 22-amino acid neurotoxic peptide originally isolated from cone snail venom. It features a compact three-disulfide bridge structure that confers exceptional stability and potent bioactivity. Primarily utilized as a selective Nav channel probe in neuroscience research, it also serves as a high-performance active ingredient in topical formulations targeting muscle relaxation and wrinkle reduction, offering a botox-alternative mechanism for cosmetic applications.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Conotoxin
CAS NO.	936616-33-0
Appearance	White to off-white lyophilized powder
Molecular Formula	C92H139N35O28S6
Molecular Weight	2375.71
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in [specific solvent(s), e.g., ultrapure water, appropriate buffers like PBS etc.]
Endotoxin	< 1.0 EU/mg
Biological Activity	The product exhibits potent inhibitory activity against [target ion channels or receptors, e.g., voltage - gated sodium channels, nicotinic acetylcholine receptors etc.].
Storage Conditions	Store at - 20°C or below in a dry and dark environment. Avoid repeated freeze - thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

This peptide functions as a pore blocker of voltage-gated sodium channels (Nav), specifically inhibiting Nav1.4 subtypes prevalent in skeletal muscle. By binding to the channel's pore region, it prevents sodium ion influx and the generation of action potentials, leading to a reversible blockade of neuromuscular transmission. This inhibition of acetylcholine release results in localized muscle paralysis, which underpins its research utility in neurophysiology and its cosmetic effect in smoothing dynamic wrinkles.

2.PRODUCT INDICATIONS

The product is indicated for academic and pharmaceutical research into sodium channel function, pain pathways, and neuromuscular disorders. In the cosmeceutical industry, it is formulated into anti-wrinkle serums, creams, and eye contour treatments aimed at reducing expression lines. It is targeted at neuroscientists, ion channel researchers, and cosmetic formulators seeking peptide-based alternatives to traditional neurotoxins for non-invasive aesthetic solutions.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical data confirms its potent paralytic activity in isolated tissue models, effectively silencing nerve-induced muscle contractions. In cosmetic efficacy studies, formulations containing this conotoxin demonstrate a significant reduction in the depth and frequency of dynamic wrinkles, such as crow's feet and forehead lines, with results observable within weeks of application. Its high selectivity minimizes off-target effects, supporting its safety profile for topical use in controlled concentrations.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: Conotoxin #MuConotoxin #CnIIIC #SodiumChannelBlocker #Neurotoxin #AntiWrinklePeptide #MarinePeptide #NeuroscienceResearch #CosmeticActive

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