Cymen-ar-ol CAS NO.39660-61-2

Cymen-ar-ol CAS NO.39660-61-2

Cymen-ar-ol   CAS NO.39660-61-2

Cymen-ar-ol CAS NO.39660-61-2

Cymen-ar-ol CAS NO.39660-61-2

Cymen-ar-ol (p-Cymen-7-ol) (CAS NO. 39660-61-2) is a high-purity, single-component monoterpenoid isolated or synthetically produced to meet exacting standards. It is a methylated derivative of the phenolic compound carvacrol, commonly found in the essential oils of oregano, thyme, and other aromatic plants. This methylation modifies its properties, typically reducing potential skin irritancy while altering its volatility and scent profile compared to carvacrol. It is a versatile material prized in the flavor & fragrance (F&F) industry for its unique aroma, in research as a tool for studying terpenoid bioactivity, and as a critical analytical reference standard. It is supplied as a colorless to pale yellow liquid.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Cymen‑ar‑ol
CAS NO.
39660‑25‑9
Appearance
White to off-white fine powder
Molecular Formula
C₁₀H₁₄O
Molecular Weight
150.22 g/mol
Purity (RP-HPLC)
≥98.0%
Solubility
Soluble in ethanol, DMSO, acetone, ethyl acetate; insoluble in water
Endotoxin
<0.1 EU/mg
Biological Activity
Broad‑spectrum antimicrobial: Effective against bacteria (e.g., Streptococcus mutans) and fungi (e.g., Candida albicans). Antioxidant: Inhibits oxidation and free radical formation. Anti‑acne & anti‑inflammatory: Reduces redness, controls sebum, prevents comedone formation. Preservative: Safe for mucosal contact; max cosmetic use level 0.1%.
Storage Conditions
Store in a cool, dry place (2–8°C); protect from light, moisture, and oxidizing agents.
Stock Location
Stock in USA
MOQ
10g


1.MECHANISM OF ACTION

  • Antimicrobial Activity (Research Focus): As a derivative of carvacrol, it is investigated for antimicrobial properties. The proposed mechanism, similar to other phenolic terpenoids, may involve:
    • Disruption of Microbial Cell Membranes: The hydrophobic molecule can integrate into lipid bilayers, increasing membrane permeability and disrupting vital functions, potentially leading to cell death or inhibited growth.

    • Inhibition of Biofilm Formation: It may interfere with the ability of microbes to form protective biofilms.

    • The methyl ether group may influence its potency, specificity, and mode of interaction with microbial targets compared to its phenolic counterparts.

  • Aromatic & Olfactory Action: In F&F applications, its mechanism is based on binding to olfactory receptors, imparting characteristic herbal, spicy, and medicinal notes.

  • Chemical Reactivity: Serves as a stable intermediate in organic synthesis for creating more complex fragrance molecules or other derivatives.


  • 2.PRODUCT INDICATIONS

  • Flavor & Fragrance Manufacturing: A key ingredient for imparting and modifying herbal, spicy, woody, and medicinal notes in fine fragrances, cosmetics, personal care products, and functional perfumery.

  • Antimicrobial & Preservative Research: Used in scientific studies to explore the structure-activity relationships (SAR) of terpenoid antimicrobials and to develop novel natural preservative systems.

  • Essential Oil & Aromatherapy Standardization: As a high-purity reference standard for Gas Chromatography-Mass Spectrometry (GC/MS) to accurately identify and quantify this component in complex natural essential oils (e.g., oregano, thyme) and commercial blends, ensuring quality and authenticity.

  • Chemical Synthesis: Utilized as a building block for the synthesis of specialty aroma chemicals and other organic compounds.


  • 3.CLINICAL EFFICACY OF PRODUCT

  • Performance Efficacy in Flavor & Fragrance: Its value is proven by its unique, stable olfactory profile and its ability to blend and fix fragrance compositions. It is recognized as safe for use in fragrances under IFRA guidelines, and its efficacy is measured by its acceptance and performance in final consumer products.

  • Research Efficacy in Antimicrobial Studies: Scientific studies utilize it to understand how chemical modification (methylation) affects the bioactivity of phenolic terpenoids. Data generated contributes to the field of natural product chemistry and the design of new antimicrobial agents, though it does not have established human clinical data itself.

  • Analytical & Quality Control Efficacy: As a reference standard, it is highly effective and essential for the accurate compositional analysis of essential oils. This is critical for quality assurance, fraud detection, and standardization in the botanical extract industry.

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