Delta-MSH CAS NO.100930-04-9
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Delta‑MSH |
| CAS NO. | 100930‑04‑9 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₃₇H₅₇N₁₁O₁₁S |
| Molecular Weight | 863.99g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water (≥10 mg/mL), dilute acetic acid, or 0.01M PBS |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Agonist at melanocortin receptors (MC1R, MC3R, MC4R, MC5R); stimulates melanin synthesis; modulates appetite and energy metabolism; anti‑inflammatory and immunomodulatory effects |
| Storage Conditions | -20°C for long‑term storage (stable for 2 years); avoid repeated freeze‑thaw cycles; store desiccated |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Delta-MSH exerts its biological effects primarily through specific binding to melanocortin receptors (MCRs), a family of G-protein-coupled receptors (GPCRs) widely distributed in skin, central nervous system, and immune tissues. Upon binding to MC1R on melanocytes, it activates the cAMP/PKA signaling pathway, which phosphorylates the microphthalmia-associated transcription factor (MITF). This phosphorylation upregulates the expression of tyrosinase, tyrosinase-related protein 1 (TRP-1), and other key enzymes in melanin synthesis, thereby promoting melanin production and skin pigmentation.
2.PRODUCT INDICATIONS
Skin pigmentation research: Exploration of melanin synthesis mechanisms, development of research tools for hypopigmentation (e.g., vitiligo) and hyperpigmentation disorders.
Metabolic disorder research: Investigation of appetite regulation pathways and potential therapeutic targets for obesity, diabetes, and metabolic syndrome.
Anti-inflammatory and immunology research: Development of novel anti-inflammatory agents for neuroinflammation, autoimmune diseases, and inflammatory skin conditions.
3.CLINICAL EFFICACY OF PRODUCT
Skin pigmentation research: Exploration of melanin synthesis mechanisms, development of research tools for hypopigmentation (e.g., vitiligo) and hyperpigmentation disorders.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
