[Des-Gly10,Dleu6, ProNHEt9] LH-RH, AcetateLeuprolide, Acetate CAS NO.74381-53-6

[Des-Gly10,Dleu6, ProNHEt9] LH-RH, AcetateLeuprolide, Acetate CAS NO.74381-53-6

[Des-Gly10,Dleu6, ProNHEt9] LH-RH, AcetateLeuprolide, Acetate CAS NO.74381-53-6

[Des-Gly10,Dleu6, ProNHEt9] LH-RH, AcetateLeuprolide, Acetate CAS NO.74381-53-6

[Des-Gly10,Dleu6, ProNHEt9] LH-RH, AcetateLeuprolide, Acetate CAS NO.74381-53-6

A synthetic peptide analog of gonadotropin-releasing hormone (GnRH), Leuprolide Acetate suppresses gonadotropin secretion via receptor desensitization, used in hormone-sensitive cancers and reproductive disorders.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
[Des-Gly10,Dleu6, ProNHEt9] LH-RH, Acetate / Leuprolide, Acetate
CAS NO.
74381-53-6
Appearance
White to off-white lyophilized powder
Molecular Formula
C₅₉H₈₄N₁₆O₁₂·C₂H₄O₂
Molecular Weight
1269.45g/mol 
Purity (RP-HPLC)
≥ 95.0%
Solubility

It is soluble in common organic solvents such as dimethyl sulfoxide (DMSO) and slightly soluble in water.

Endotoxin< 1.0 EU/mg
Biological Activity
[Des-Gly10,Dleu6, ProNHEt9] LH - RH, Acetate / Leuprolide, Acetate is a potent agonist of the LH - RH receptor. It binds to the receptor with high affinity, leading to the down - regulation of gonadotropin secretion.
Storage Conditions
The product should be stored at - 20°C in a dry and dark environment. 
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

GnRH Receptor Agonist: Binds pituitary GnRH receptors, initially stimulating LH/FSH release.
Downregulation: Prolonged binding inhibits gonadotropin synthesis, reducing testosterone/estrogen levels.
Hormonal Suppression: Clinically effective for prostate cancer, endometriosis, and precocious puberty.


    2.PRODUCT INDICATIONS

    Oncology: Metastatic prostate cancer, breast cancer (hormone receptor-positive).
    Reproductive Health: Endometriosis, uterine fibroids, precocious puberty.
    Assisted Reproduction: Ovulation induction in IVF protocols.


    3.CLINICAL EFFICACY OF PRODUCT

    Prostate Cancer: Reduces testosterone to castration levels (~90% efficacy).
    Endometriosis: 70-90% symptom relief in 6 months.
    Pediatrics: Normalizes growth in central precocious puberty.


    4.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
    Professional and Secure Packaging
    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
    We can also customize packaging according to customer needs.
    Shipping Methods 
    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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