Name: Edoxaban CAS 480449-70-5: Effective Anticoagulant Therapy
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Edoxaban CAS NO.480449-70-5

Edoxaban is an oral, direct Factor Xa inhibitor belonging to the class of Direct Oral Anticoagulants (DOACs), marketed under brand names such as Lixiana and Savaysa. It is characterized by once-daily dosing, predictable pharmacokinetics, and no routine requirement for coagulation monitoring, offering a convenient alternative to traditional warfarin therapy for long-term thrombotic risk management in eligible adult populations.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Edoxaban
CAS NO.	480449-70-5
Appearance	White to off-white powder
Molecular Formula	C₂₄H₃₀ClN₇O₄S
Molecular Weight	547.97 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in DMSO, slightly soluble in water; insoluble in ethanol
Endotoxin	< 0.001 EU/mg (as applicable for research use)
Biological Activity	Potent, selective, reversible inhibitor of Factor Xa
Storage Conditions	Store at -20°C, protected from light and moisture
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Edoxaban exerts its anticoagulant effect by selectively and reversibly inhibiting Factor Xa (both free and clot-bound) in the final common pathway of the coagulation cascade. By binding directly to the active site of Factor Xa, it prevents the conversion of prothrombin to thrombin, thereby reducing thrombin burst and subsequent fibrin clot formation. This mechanism is independent of antithrombin III and results in a concentration-dependent prolongation of clotting times, effectively suppressing thrombus generation without directly affecting platelet aggregation.

2.PRODUCT INDICATIONS

Edoxaban is indicated for the prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation (NVAF) who have one or more risk factors (e.g., prior stroke, heart failure, hypertension, age ≥75). It is also approved for the treatment of acute deep vein thrombosis (DVT) and pulmonary embolism (PE), as well as the prevention of recurrent venous thromboembolism (VTE), following an initial period of parenteral anticoagulation.

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3.CLINICAL EFFICACY OF PRODUCT

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: Edoxaban #FactorXaInhibitor #OralAnticoagulant #Lixiana #Savaysa #StrokePrevention #VTEtreatment #DOAC

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