Exenatide Acetate CAS NO.141732-76-5/141758-74-9
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Exenatide Acetate |
| CAS NO. | 141732-76-5/141758-74-9 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C184H282N50O60S |
| Molecular Weight | 4186.66 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in water; slightly soluble in dilute acid solutions |
| Endotoxin | < 0.1 EU/mg |
| Biological Activity | Potent GLP-1 receptor agonist; enhances glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying, and promotes satiety |
| Storage Conditions | Store at -20°C, protected from light; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Exenatide Acetate exerts its effects by binding to and activating the GLP-1 receptor on pancreatic beta cells, which triggers a glucose-dependent increase in insulin secretion while simultaneously suppressing glucagon release. Beyond pancreatic actions, it slows gastric emptying and acts centrally on the hypothalamus to promote satiety and reduce appetite, thereby providing a multi-faceted approach to glycemic control and energy balance that is intrinsically linked to blood glucose levels, minimizing the risk of hypoglycemia.
2.PRODUCT INDICATIONS
This product is indicated for use as a critical research tool in the investigation of Type 2 Diabetes Mellitus, particularly for patients inadequately controlled by metformin, sulfonylureas, or thiazolidinediones. It is also utilized in preclinical studies exploring its neuroprotective effects in models of Parkinson's and Alzheimer's disease, as well as its potential role in cardiovascular protection and weight management, serving as a reference standard for the development of next-generation GLP-1-based therapies.
3.CLINICAL EFFICACY OF PRODUCT
Clinical trials have demonstrated that Exenatide Acetate significantly reduces HbA1c levels by 0.5% to 1.0% and promotes progressive weight loss of 2 to 5 kg over 30 weeks to 3 years of treatment. Its efficacy is sustained in long-term extensions, showing durable glycemic control and progressive body weight reduction, with the added benefit of improving beta-cell function and lipid profiles, making it a valuable therapeutic option for achieving composite treatment goals in Type 2 Diabetes management.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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