Fisetin CAS NO.528-48-3

Fisetin CAS NO.528-48-3

Fisetin CAS NO.528-48-3

Fisetin CAS NO.528-48-3

Fisetin CAS NO.528-48-3

Fisetin is a potent natural senolytic flavonoid extracted from strawberries, apples, and the smoke tree (Cotinus coggygria). This high-purity supplement is specifically formulated to target cellular aging by clearing senescent "zombie cells," reducing chronic inflammation, and protecting neurological function. It is designed for health-conscious adults seeking to support longevity, cognitive clarity, and overall cellular rejuvenation, available in vegan-friendly capsules with enhanced bioavailability formulations for optimal absorption.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Fisetin
CAS NO.
528-48-3
Appearance
Yellow to orange crystalline powder
Molecular Formula
C15H10O6
Molecular Weight
286.24 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility

Soluble in DMSO, ethanol, and slightly soluble in water; insoluble in non – polar organic solvents like hexane

Endotoxin≤0.5 EU/mg 
Biological Activity
Exhibits senolytic activity by selectively eliminating senescent cells, activates Nrf2 pathway to enhance antioxidant defense, modulates sirtuin (SIRT1) activity to regulate cellular metabolism and aging – related processes, and has anti – inflammatory effects by inhibiting NF – κB signaling
Storage Conditions
Store in a cool, dry place at 2 – 8°C, protected from light and moisture; avoid long – term exposure to air
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Fisetin works primarily as a senolytic agent by selectively inducing apoptosis in senescent cells—dysfunctional cells that accumulate with age and contribute to tissue decline—while sparing healthy ones. It modulates key longevity pathways including SIRT1 activation and mTOR inhibition, while also functioning as a powerful Nrf2 activator to boost endogenous antioxidant defenses and mitigate oxidative stress at the cellular level.

upload/attachment/image/202603/27/1774577858e1505b4951c3ac017a67f4e831395bc5_local.png

2.PRODUCT INDICATIONS

This product is indicated for individuals targeting age-related cellular decline, including those seeking to reduce frailty, support joint health, and maintain skin elasticity. It is also aimed at users focusing on brain health, particularly for memory support and neuroprotection against cognitive decline, as well as those managing metabolic wellness through natural anti-inflammatory and antioxidant support without pharmaceutical interventions.

upload/attachment/image/202603/27/1774577928419559ee7c22aa0577955f1f1345ce1e_local.png

3.CLINICAL EFFICACY OF PRODUCT

Human clinical trials, such as the FISET-AGE study, demonstrate that Fisetin supplementation significantly reduces biomarkers of cellular senescence and inflammation, with data showing improved physical function and walking speed in older adults. Early-phase trials in neuroprotection report enhancements in cognitive scores, supported by preclinical evidence of lifespan extension and robust senolytic activity that clears a majority of senescent cells in model organisms.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

upload/attachment/image/202603/11/17731937213fbed5ed3f3869d1613bb629f6365f21_local.png


5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

upload/attachment/image/202601/20/1768872924be74a0641f7ddbf20e541c97f2066c5c_local.jpg


Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags:Fisetin, Senolytic, AntiAging, Longevity, CellularHealth, BrainHealth, Flavonoid, NAD, Sirt1, Nrf2, ZombieCells, Healthspan, LifeExtension, NaturalSupplement, CognitiveFunction, Supplier, Manufacturer, Bulk order,  Pharmaceutical.


If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553

Premium API Oxandrolone Ucinky Manufacturing
May 25, 26
Premium API Oxandrolone Ucinky Manufacturing
Premium API Oxandrolone Ucinky Manufacturing Leading global supplier of high-purity chemical raw materials for pharmaceutical grade Oxandrolone Ucinky, combining precision engineering with industrial scale. 5000 kg Annual Output 120 Countries Served 5 Days Sample Lead Time 99.7 On-Time Delivery Industrial Precision Pure Chemical Synthesis Engineering the future of pharmaceutical intermediates with unmatched stability. Our facility stands as a global leader in the oxandrolone ucinky sector, utilizing CRYOGENIC CRYSTALLIZATION and advanced chromatography to ensure an assay purity exceeding 99.8. We integrate a fully automated closed-loop system that eliminates human error and contamination.
Clinical Benefits and Applications of Oxandrolone Therapy
May 22, 26
Clinical Benefits and Applications of Oxandrolone Therapy
Oxandrolone therapy represents a sophisticated intersection of endocrine science and regenerative medicine, primarily utilized to address muscle wasting and metabolic dysfunction. In the global pharmaceutical landscape, this specific approach to androgen therapy is valued for its unique ability to promote protein synthesis while exhibiting a lower androgenic profile compared to traditional steroids, making it a critical tool for patients recovering from severe trauma or chronic illness. From a clinical perspective, understanding the nuances of oxandrolone therapy is essential for optimizing patient outcomes in weight gain and tissue repair.
Clinical Benefits and Production of Oxandrolone Steroid
May 20, 26
Clinical Benefits and Production of Oxandrolone Steroid
The global pharmaceutical landscape has seen a significant rise in the demand for highly specialized anabolic agents, among which the oxandrolone steroid stands out due to its unique chemical profile and therapeutic versatility. As a modified version of dihydrotestosterone, this compound provides a potent means of addressing muscle wasting and metabolic deficits, making it a critical asset in both clinical rehabilitation and advanced physiological research. Understanding the nuances of this synthetic compound is essential for healthcare providers and researchers alike, as it balances efficacy with a relatively lower androgenic profile compared to other steroids.

If you are interested in our products, you can choose to leave your information here, and we will be in touch with you shortly.