Ganirelix acetate CAS NO.123246-29-7/124904-93-4

Ganirelix acetate CAS NO.123246-29-7/124904-93-4

Ganirelix acetate CAS NO.123246-29-7/124904-93-4

Ganirelix acetate CAS NO.123246-29-7/124904-93-4

Ganirelix acetate CAS NO.123246-29-7/124904-93-4

Ganirelix Acetate is a highly potent and selective injectable GnRH antagonist specifically formulated for use in controlled ovarian stimulation (COS) protocols during assisted reproductive technology (ART) cycles. This ready-to-use solution is designed for precise subcutaneous administration, offering a rapid and reversible suppression of gonadotropin release to prevent premature luteinizing hormone (LH) surges. It is a critical component in modern fertility treatments, particularly for women undergoing in vitro fertilization (IVF), ensuring optimal timing for egg retrieval by maintaining hormonal control without the initial flare effect associated with agonists. The product is supplied as a sterile, prefilled syringe, facilitating accurate dosing and convenience in clinical settings.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Ganirelix acetate
CAS NO.
123246-29-7/124904-93-4
Appearance
White to off-white lyophilized powder
Molecular Formula
C80H113C1N18O13
Molecular Weight
1570.41 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility
Soluble in water; reconstitutes in sterile diluent for injection
Endotoxin≤50 EU/mg 
Biological Activity
Potent GnRH antagonist; inhibits LH surge in ovarian stimulation protocols
Storage Conditions
Store at 2–8°C, protected from light; do not freeze
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Ganirelix Acetate functions as a competitive antagonist at the gonadotropin-releasing hormone (GnRH) receptors located in the pituitary gland. By binding directly to these receptors, it blocks the action of endogenous GnRH, leading to an immediate and pronounced suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion. This mechanism is characterized by its rapid onset of action and the absence of an initial "flare-up" or stimulation phase, which allows for a more controlled and predictable down-regulation of the hypothalamic-pituitary-gonadal axis. The effect is dose-dependent and reversible upon discontinuation, enabling a quick recovery of normal pituitary function after the treatment cycle is completed.

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2.PRODUCT INDICATIONS

This product is clinically indicated for the prevention of premature ovulation in women undergoing controlled ovarian hyperstimulation as part of an IVF or intracytoplasmic sperm injection (ICSI) program. It is specifically tailored for patients who require a short and flexible treatment protocol to inhibit an untimely LH surge that could compromise the success of egg retrieval. The target user group primarily includes women of reproductive age facing infertility challenges, where the goal is to synchronize follicle development and prevent the release of immature oocytes. Its use is integral to antagonist cycles, providing a crucial window for the administration of human chorionic gonadotropin (hCG) trigger and subsequent oocyte collection.

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3.CLINICAL EFFICACY OF PRODUCT

Clinical studies and extensive real-world use have demonstrated that Ganirelix Acetate significantly reduces the incidence of premature LH surges, thereby increasing the number of mature oocytes retrieved and improving fertilization rates in IVF/ICSI cycles. Its efficacy is comparable to that of long agonist protocols but with a substantially shorter duration of treatment, reduced total gonadotropin consumption, and a lower risk of ovarian hyperstimulation syndrome (OHSS). The product's rapid suppression profile ensures a high degree of cycle control, contributing to improved embryo quality and consistent pregnancy outcomes, making it a preferred choice for many fertility specialists seeking to optimize patient comfort and clinical success.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


HotTags:Ganirelix, GanirelixAcetate, GnRHAntagonist, IVF, Fertility, FertilityTreatment, IVFMedication, IVFCycle, EggRetrieval, ReproductiveHealth, Infertility, ART, AssistedReproduction, Orgalutran, Antagon, LHSuppression, OvarianStimulation, Supplier, Manufacturer, Bulk order,  Pharmaceutical.


If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553

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