Gastrin Releasing Peptide-Lys(Biotin), human CAS NO.93755-85-2
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Gastrin Releasing Peptide-Lys(Biotin), human |
| CAS NO. | 93755-85-2 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C130H204N38O31S2 |
| Molecular Weight | 2859.3g/mol |
| Amino Acid Sequence | Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys(Biotin)-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH₂ (human GRP sequence with Lys‑biotin) |
| Purity (RP-HPLC) | ≥95.0% (customizable to ≥98.0%) |
| Solubility | Soluble in water, PBS, or dilute acetic acid solution; may require brief sonication |
| Endotoxin | <1.0 eu=""> |
| Biological Activity | Biotinylated analogue of gastrin‑releasing peptide (GRP); binds to GRP receptor (bombesin receptor subtype 2) for detection, pull‑down, or imaging studies in cancer and neuroendocrine research. |
| Storage Conditions | Store at –20°C, protected from light and moisture. Avoid repeated freeze‑thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1mg |
1.MECHANISM OF ACTION
This peptide functions as a high-affinity ligand for the Gastrin-Releasing Peptide Receptor (GRPR), initiating intracellular signaling cascades that stimulate the release of gastrin and other regulatory peptides. The site-specific biotin label enables its application in advanced detection and visualization techniques without significantly altering its native receptor-binding profile.
2.PRODUCT INDICATIONS
Gastrin Releasing Peptide-Lys(Biotin), human is used in receptor binding studies, immunoassays, flow cytometry, and imaging applications related to oncology, gastroenterology, and neuroendocrinology. It is a key tool for the detection, quantification, and functional analysis of GRPR expression in both normal and pathological tissues.
3.CLINICAL EFFICACY OF PRODUCT
As a research-grade detection reagent, this peptide enables highly sensitive and specific identification of GRPR-positive cells. Its reliable performance in preclinical models aids in understanding receptor distribution and function, thereby supporting the development of diagnostic and therapeutic strategies for GRPR-associated cancers and disorders.
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Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
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Shipping Methods
Main Method: International Air Freight
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