Gastrin Tetrapeptide CAS NO.35144-91-3
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Gastrin Tetrapeptide |
| CAS NO. | 35144-91-3 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C29H36N6O6S |
| Molecular Weight | 596.71g/mol |
| Amino Acid Sequence | Trp-Met-Asp-Phe-NH₂ (corresponding to the C‑terminal tetrapeptide of gastrin) |
| Purity (RP-HPLC) | ≥95.0% (can be customized to ≥98.0%) |
| Solubility | Soluble in water, dilute acetic acid solution, and aqueous buffers (e.g., PBS) |
| Endotoxin | <1.0 eu=""> |
| Biological Activity | Minimal gastrin‑like bioactivity; primarily used as a reference standard or blocking peptide in gastrin receptor and immunoassay studies. |
| Storage Conditions | Store at –20°C, protected from light and moisture. |
| Stock Location | Stock in USA |
| MOQ | 1mg |
1.MECHANISM OF ACTION
Gastrin Tetrapeptide functions by binding to cholecystokinin-2/gastrin receptors (CCK2R), mimicking the activity of full-length gastrin to stimulate gastric acid secretion and promote mucosal cell growth.
2.PRODUCT INDICATIONS
This peptide is applied in studies of gastric physiology, acid secretion regulation, and as a reference standard or blocking agent in gastrin-related immunoassays and receptor binding experiments.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical research confirms that Gastrin Tetrapeptide effectively induces acid secretion and supports mucosal proliferation in experimental models, validating its utility as a tool for investigating gastrin-mediated pathways in gastrointestinal health and disease.
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