Genkwanin CAS NO.437-64-9
TECHNICAL SPECIFICATIONS
Item | Specification |
|---|---|
Product Name | Genkwanin |
CAS NO. | 437-64-9 |
Appearance | White to off-white crystalline powder |
Molecular Formula | C₁₆H₁₂O₅ |
Molecular Weight | 284.26 g/mol |
Amino Acid Sequence | Not applicable |
Purity (RP-HPLC) | ≥98.0% |
Solubility | Soluble in DMSO and methanol; insoluble in water |
Endotoxin | < 1 EU/mg |
Biological Activity | Exhibits significant anti-inflammatory, antioxidant, anti-tumor, and anti-estrogenic activities; known for inhibiting NF-κB and MAPK signaling pathways |
Storage Conditions | Store at -20°C, protected from light and moisture |
Stock Location | USA / Germany / China (optional, based on actual stock) |
MOQ | 1 mg |
1.Mechanism of Action
Genkwanin exerts its biological effects through multiple mechanisms, primarily by modulating key cellular signaling pathways such as NF-κB, MAPK, and PI3K/Akt, which regulate inflammation, apoptosis, and cell proliferation; it also acts as an estrogen receptor modulator, influencing hormonal balance and exerting neuroprotective and cardioprotective effects through antioxidant mechanisms.
2.Product Indications
This compound is indicated for research purposes in oncology for its potential anti-tumor activity, in inflammatory and autoimmune disease studies due to its potent anti-inflammatory properties, in neurological research for neuroprotection, and in endocrine studies exploring its anti-estrogenic and hormonal regulation effects, making it suitable for academic, biotech, and pharmaceutical researchers.
3.Clinical Efficacy of Product
While clinical efficacy in humans is still under investigation, preclinical studies have demonstrated genkwanin's effectiveness in reducing tumor growth, suppressing inflammatory responses, protecting neuronal cells from oxidative damage, and modulating estrogenic activity, showing promising results in animal models and in vitro assays, which supports its potential for future therapeutic applications in cancer, inflammation, and neurodegenerative diseases.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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