GHK-Cu CAS NO.89030-95-5

GHK-Cu CAS NO.89030-95-5

GHK-Cu CAS NO.89030-95-5

GHK-Cu CAS NO.89030-95-5

GHK-Cu CAS NO.89030-95-5

GHK-Cu (CAS NO. 89030-95-5) is a naturally occurring, high-purity copper peptide complex composed of the tripeptide Gly-His-Lys (GHK) bound to a copper(II) ion. This biomimetic peptide is a master regulator of tissue repair and regeneration with proven anti-aging, wound healing, and antioxidant properties. It is widely utilized in advanced cosmetic formulations, nutraceuticals, and biomedical research to promote skin rejuvenation, hair growth, and tissue regeneration. This product is supplied as a stable, blue lyophilized powder, ensuring optimal bioavailability and efficacy.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
GHK-Cu 
CAS NO.
89030-95-5
Appearance
Bule to off-bule  lyophilized powder
Molecular Formula
C₁₄H₂₁CuN₆O₄
Molecular Weight
 400.91 g/mol
Purity (RP-HPLC)
≥95%
Solubility

Soluble in water (≥100 mg/mL); soluble in aqueous buffers (PBS, Tris-HCl); insoluble in non-polar solvents.

Endotoxin≤1.0 EU/mg
Biological Activity
Copper-dependent matrikine signal complex. Stimulates collagen I/III/IV, elastin, fibronectin, and glycosaminoglycan synthesis; promotes tissue remodeling, wound repair, and angiogenesis.
Storage Conditions
Store at 2–8°C for short-term (6 months); -20°C for long-term (2+ years) in a dry, light-protected container. Avoid repeated freeze-thaw cycles; protect from oxidation.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

GHK-Cu operates through multiple biochemical pathways:

  • Tissue Remodeling: Binds to specific receptors on fibroblasts and keratinocytes, upregulating genes involved in extracellular matrix (ECM) synthesis, including collagen (I, III, IV), elastin, and glycosaminoglycans.

  • Anti-inflammatory: Reduces levels of pro-inflammatory cytokines (e.g., TNF-α, IL-6), modulates NF-κB signaling, and inhibits mast cell degranulation.

  • Antioxidant Defense: Chelates copper ions to prevent Fenton reactions and directly scavenges free radicals.

  • Angiogenesis and Wound Healing: Stimulates blood vessel formation and enhances tissue repair by increasing cell migration and proliferation.

  • Gene Expression Regulation: Modulates the expression of over 4,000 human genes, shifting cellular activity toward a younger, healthier state.

2.PRODUCT INDICATIONS

GHK-Cu is applied across a broad range of fields:
  • Cosmetic & Skincare: Used in anti-aging serums, creams, and lotions to improve skin elasticity, firmness, and reduce wrinkles.

  • Wound Care & Dermatology: Incorporated into formulations for burns, scars, and ulcers to accelerate healing and reduce scar formation.

  • Hair Growth Products: Stimulates hair follicles and promotes hair regrowth in topical solutions.

  • Nutraceuticals: Used in oral supplements for systemic anti-aging, joint health, and tissue repair.

  • Biomedical Research: Studied for its role in tissue engineering, regenerative medicine, and age-related diseases.

3.CLINICAL EFFICACY OF PRODUCT

Clinical and preclinical studies demonstrate that GHK-Cu:

  • Significantly improves skin elasticity, firmness, and hydration while reducing fine lines and wrinkles.

  • Accelerates wound healing and reduces scar formation in burns, surgical wounds, and diabetic ulcers.

  • Promotes hair growth in individuals with androgenetic alopecia.

  • Exhibits systemic anti-inflammatory and tissue-protective effects when taken orally.

  • Is well-tolerated and safe for topical and oral use.
     
    4.Certificate

    GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

     

    Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

     

    We prioritize:

  • 1.A rigorous quality management system

    2.Batch traceability and stability data

    3.Professional laboratory testing and validation

    4.Compliance with international trade standards


    Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.


5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags: cosmetic peptide, drugpeptides,weightlosspeptide,suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, high quality, free sample,Bivalirudin Trifluoroacetate


If you have any product requirements, please send an email to:business@huanqiukeji9.com.WhatsAPP:+852 7084 6510


What Does GHK-Cu Peptide Do?


GHK-Cu peptide is a naturally occurring copper complex made up of the tripeptide glycyl-L-histidyl-L-lysine bound to a copper ion. It is found in human plasma, saliva, and urine, and its levels are known to decline with age. Because of its biological activity, it has attracted significant interest in dermatology, regenerative medicine, and cosmetic science.


The primary function of GHK-Cu is its role in supporting tissue repair and cellular regeneration. It has been shown in research to influence gene expression in ways that promote healing and restore normal cellular function. One of its most studied effects is the stimulation of collagen, elastin, and glycosaminoglycan production, which are essential components of healthy skin and connective tissue. As a result, it is often associated with improved skin firmness, elasticity, and overall texture.


GHK-Cu also has antioxidant and anti-inflammatory properties. It can help reduce oxidative stress by modulating metal ions and supporting the body’s natural defense systems against free radicals. This contributes to its potential role in slowing visible signs of skin aging, such as wrinkles and loss of elasticity. In addition, it may help regulate inflammatory responses, which is important for wound healing and tissue repair.


Another important function of GHK-Cu is its ability to support angiogenesis, the formation of new blood vessels. This process improves oxygen and nutrient delivery to damaged tissues, further enhancing healing. Some studies also suggest it may influence hair follicle activity, potentially supporting hair growth in certain conditions, although this area is still being researched.


Overall, GHK-Cu peptide is considered a multifunctional biological modulator rather than a single-target compound. Its effects are broad, involving skin regeneration, antioxidant defense, and tissue repair pathways. While it is widely used in cosmetic and skincare formulations, ongoing research continues to explore its full therapeutic potential in medical applications.


GHK-Cu Peptide Before and After

 

GHK-Cu peptide is often discussed in “before and after” contexts because of its reported effects on skin quality, wound healing, and overall tissue appearance, especially in cosmetic and dermatological applications. Before use, skin or tissue conditions typically associated with aging or damage may include fine lines, wrinkles, uneven texture, reduced elasticity, and dull tone. These changes are largely linked to decreased collagen production, slower cell turnover, and reduced regenerative capacity over time. In some cases, minor scars or sun damage may also appear more prominent due to weakened structural support in the skin.


After consistent exposure to GHK-Cu, either through topical formulations or experimental treatments, users in studies and cosmetic reports often describe noticeable improvements in skin appearance and quality. One of the most commonly reported changes is increased firmness and elasticity, which is associated with its ability to stimulate collagen and elastin synthesis. Skin may appear smoother, more hydrated, and more even in tone due to improved cellular repair and regeneration processes. Fine lines can look reduced, and overall skin texture may become softer and more refined.


In addition to visible cosmetic changes, GHK-Cu is also associated with enhanced wound healing responses. Small cuts, irritation, or post-inflammatory marks may show faster recovery and reduced scarring in experimental settings. This is believed to be linked to its influence on growth factors, antioxidant activity, and support for angiogenesis, which improves blood supply to healing tissues.


However, it is important to note that “before and after” results can vary widely depending on concentration, formulation, duration of use, and individual biological differences. While early research and cosmetic observations are promising, GHK-Cu is not a guaranteed or uniform anti-aging solution, and more clinical studies are still needed to fully confirm its long-term effects.


GHK-Cu Peptide Where to Get


GHK-Cu peptide is widely available, but where you can get it depends heavily on its intended use and legal status in your country. In general, it is sold in three main forms: cosmetic skincare products, research-grade powders, and medically supervised formulations.


The most accessible and legal option for most people is cosmetic skincare products. Many anti-aging creams and serums contain GHK-Cu (often listed as copper tripeptide-1). These products can be purchased from reputable skincare brands, dermatology clinics, and online beauty retailers. This form is designed for topical use and is regulated as a cosmetic ingredient, meaning it does not require a prescription. It is considered the safest and most widely available way to obtain GHK-Cu.


A second category is research-grade GHK-Cu sold by peptide or laboratory supply companies. These are typically labeled “for research use only” and are not approved for human consumption or injection. Such products are often purchased by laboratories for experimental studies. While they may be legally sold in some regions, they exist in a regulatory gray area, and quality can vary significantly depending on the supplier. Recent industry reviews emphasize the importance of third-party testing and certificates of analysis to verify purity and safety.


In some countries, GHK-Cu may also be available through licensed medical or compounding clinics, but this is less common and usually limited to topical prescription formulations under professional supervision.

However, it is important to be cautious with online vendors, as unregulated peptide markets can include counterfeit or low-quality products. Experts warn that improperly sourced peptides may carry risks such as contamination or incorrect composition.


Overall, the safest and most practical way to “get” GHK-Cu is through regulated cosmetic skincare products, while other forms should only be considered with proper medical or research oversight.

Premium API Oxandrolone Ucinky Manufacturing
May 25, 26
Premium API Oxandrolone Ucinky Manufacturing
Premium API Oxandrolone Ucinky Manufacturing Leading global supplier of high-purity chemical raw materials for pharmaceutical grade Oxandrolone Ucinky, combining precision engineering with industrial scale. 5000 kg Annual Output 120 Countries Served 5 Days Sample Lead Time 99.7 On-Time Delivery Industrial Precision Pure Chemical Synthesis Engineering the future of pharmaceutical intermediates with unmatched stability. Our facility stands as a global leader in the oxandrolone ucinky sector, utilizing CRYOGENIC CRYSTALLIZATION and advanced chromatography to ensure an assay purity exceeding 99.8. We integrate a fully automated closed-loop system that eliminates human error and contamination.
Clinical Benefits and Applications of Oxandrolone Therapy
May 22, 26
Clinical Benefits and Applications of Oxandrolone Therapy
Oxandrolone therapy represents a sophisticated intersection of endocrine science and regenerative medicine, primarily utilized to address muscle wasting and metabolic dysfunction. In the global pharmaceutical landscape, this specific approach to androgen therapy is valued for its unique ability to promote protein synthesis while exhibiting a lower androgenic profile compared to traditional steroids, making it a critical tool for patients recovering from severe trauma or chronic illness. From a clinical perspective, understanding the nuances of oxandrolone therapy is essential for optimizing patient outcomes in weight gain and tissue repair.
Clinical Benefits and Production of Oxandrolone Steroid
May 20, 26
Clinical Benefits and Production of Oxandrolone Steroid
The global pharmaceutical landscape has seen a significant rise in the demand for highly specialized anabolic agents, among which the oxandrolone steroid stands out due to its unique chemical profile and therapeutic versatility. As a modified version of dihydrotestosterone, this compound provides a potent means of addressing muscle wasting and metabolic deficits, making it a critical asset in both clinical rehabilitation and advanced physiological research. Understanding the nuances of this synthetic compound is essential for healthcare providers and researchers alike, as it balances efficacy with a relatively lower androgenic profile compared to other steroids.

If you are interested in our products, you can choose to leave your information here, and we will be in touch with you shortly.