GLP-1 (7-37) Acetate CAS NO.106612-94-6
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | GLP-1 (7-37) Acetate |
| CAS NO. | 106612-94-6 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C151H228N40O47 |
| Molecular Weight | 3355.74 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water, 1% acetic acid, or DMSO (reconstitute as needed) |
| Endotoxin | < 0.1 EU/mg |
| Biological Activity | Stimulates glucose-dependent insulin secretion; activates GLP-1R in vitro and in vivo models |
| Storage Conditions | Store at -20°C, protected from light; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
GLP-1 (7-37) Acetate functions as a potent incretin mimetic by selectively binding to and activating the GLP-1 receptor (GLP-1R), a class B G-protein coupled receptor predominantly expressed on pancreatic beta cells. Upon receptor activation, it triggers intracellular cAMP signaling pathways that enhance glucose-dependent insulin secretion, meaning it stimulates insulin release only in the presence of elevated blood glucose levels, thereby minimizing the risk of hypoglycemia. Additionally, this mechanism suppresses glucagon secretion, slows gastric emptying, and promotes satiety, making it a multifaceted tool for studying metabolic regulation.
2.PRODUCT INDICATIONS
This product is indicated for scientific research applications, specifically in the fields of type 2 diabetes, obesity, and metabolic syndrome. It serves as a critical reagent for in vitro assays (e.g., receptor binding studies, cell signaling experiments) and in vivo animal models (e.g., hyperglycemic clamp studies in rodents) to investigate the pathophysiology of diabetes and evaluate potential anti-diabetic agents. Researchers in academic institutions, pharmaceutical companies, and biotech R&D departments utilize it to explore mechanisms of beta-cell protection, appetite regulation, and weight management.
3.CLINICAL EFFICACY OF PRODUCT
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
HotTags:GLP1, GLP1R agonist, peptide, insulin secretion, diabetes research, obesity research, metabolic disease, incretin, research chemical, in vitro, in vivo, preclinical, scientific research, not for human use, lyophilized powder, acetate salt, HY-P0055A, 1450806-98-0, Supplier, Manufacturer, Bulk order, Pharmaceutical.
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