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GM-CSF (96-112)

GM-CSF (96-112)

GM-CSF (96-112)

GM-CSF (96-112)

GM-CSF (96-112)

This high – purity Granulocyte – Macrophage Colony – Stimulating Factor (GM – CSF, 96 – 112) features a molecular formula of C₈₈H₁₃₉N₂₁O₂₉S and a molecular weight of 1986.27 g/mol. Ideal for biomedical research and therapeutic applications, it supports immune modulation and hematopoietic cell development.

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TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
GM-CSF (96-112)
CAS NO.
\
Appearance
White to off-white lyophilized powder
Molecular Formula
C₈₈H₁₃₉N₂₁O₂₉S
Molecular Weight
1986.27g/mol 
Purity (RP-HPLC)
≥95%
Solubility

Soluble in water or appropriate buffer solutions

Endotoxin≤1.0 EU/mg
Biological Activity
GM – CSF stimulates the production, differentiation, activation, and survival of granulocytes and macrophages. It plays a crucial role in the immune response by promoting hematopoiesis and enhancing the function of myeloid cells.
Storage Conditions
Store at – 20°C or below in a dry environment. Avoid repeated freeze – thaw cycles.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

GM – CSF functions as a cytokine. It binds to specific receptors on the surface of hematopoietic stem cells, progenitor cells, as well as mature myeloid cells. This binding activates intracellular signaling pathways that lead to cell proliferation, differentiation, and survival. In particular, it stimulates the production of granulocytes and macrophages from bone – marrow precursors. It also enhances the functional activities of mature granulocytes and macrophages, including phagocytosis, antigen presentation, and the secretion of various inflammatory mediators.


    2.PRODUCT INDICATIONS

    Oncology: Reduces infection risk in cancer patients undergoing chemotherapy (prevents febrile neutropenia).
    Hematology: Treats neutropenia and other myeloid cell deficiencies.
    Immunotherapy: Boosts anti-tumor immune responses via activated macrophages and dendritic cells.


    3.CLINICAL EFFICACY OF PRODUCT

    Accelerates neutrophil recovery post-chemotherapy, reducing hospitalization duration and mortality.
    Proven to restore immune cell counts within 24–72 hours in clinical trials.
    Supports adaptive immune activation for enhanced cancer immunotherapy outcomes.


    4.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
    Professional and Secure Packaging
    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
    We can also customize packaging according to customer needs.
    Shipping Methods 
    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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