Name: Gn-RH Associated Peptide (GAP) (1-13) Human CAS 100111-07-7
Availability: InStock
Rating: 4.5 (89 reviews)

Gn-RH Associated Peptide (GAP) (1-13), human CAS NO.100111-07-7

Gn-RH Associated Peptide (GAP) (1-13), human is a synthetic 13-amino acid peptide fragment derived from the C-terminal region of the GnRH precursor protein. This research-grade peptide represents the N-terminal portion of the full-length GAP peptide, providing a specific tool for studying the structure and potential functions of this neuroendocrine-associated peptide. Manufactured under stringent quality controls with HPLC-verified purity and comprehensive analytical documentation, this product enables researchers to investigate GAP's role in neuroendocrine regulation, receptor interactions, and reproductive physiology. While the complete biological functions of GAP remain under investigation, this peptide serves as a valuable reagent for antibody development, receptor binding studies, and functional characterization of this less-explored neuropeptide.

Send Email

Download

TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Gn-RH Associated Peptide (GAP) (1-13), human
CAS NO.	100111-07-7
Appearance	White to off-white lyophilized powder
Molecular Formula	C65H101N15O25
Molecular Weight	1492.6g/mol
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in water, dilute acetic acid (0.1%), PBS (pH 7-8)
Endotoxin	< 1.0 EU/mg
Biological Activity	A peptide fragment associated with the gonadotropin-releasing hormone (GnRH) precursor protein; it may be involved in neuroendocrine regulation, but its specific function is still under investigation and it is mainly used as a research tool.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The mechanism of action for Gn-RH Associated Peptide (GAP) (1-13) is not fully established, as the complete biological functions of GAP are still under investigation. Current research suggests that GAP may interact with specific receptors in the hypothalamus and pituitary, potentially modulating neuroendocrine signaling pathways. The (1-13) fragment may retain some binding properties of the full-length GAP, though its activity is likely reduced compared to the complete peptide. Proposed mechanisms include potential modulation of prolactin secretion, interaction with G-protein coupled receptors, or allosteric regulation of other neuropeptide systems. However, these mechanisms remain speculative and require further validation. This peptide primarily serves as a research tool to explore these potential interactions and characterize receptor binding properties.

2.PRODUCT INDICATIONS

Neuroendocrine Research: Investigation of GAP's potential role in hypothalamic-pituitary axis regulation

Receptor Binding Studies: Characterization of potential GAP receptor interactions and binding kinetics

Antibody Development: Production of specific antibodies against GAP epitopes for immunoassays

Peptide Structure-Function Studies: Exploration of how specific GAP fragments contribute to biological activity

Reproductive Physiology: Research on potential roles in reproductive hormone regulation

Neuropeptide Research: Comparative studies with other neuroendocrine peptides

3.CLINICAL EFFICACY OF PRODUCT

Sequence Accuracy: Verified 13-amino acid sequence corresponding to human GAP (1-13)

Research Reliability: Consistent performance in antibody production and binding assays

Quality Documentation: Certificate of Analysis provided with purity, mass spec, and analytical data

Technical Support: Access to application guidance for neuropeptide research

Custom Synthesis Capability: Support for additional modifications or bulk quantities

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.