HBV polymerase (455 – 463)
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | HBV polymerase (455-463) |
| CAS NO. | |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C46H79N15O12 |
| Molecular Weight | 1034.24/mol |
| Amino Acid Sequence | FLPSDFFPSV (HBV polymerase residues 455-463, HLA-A*0201-restricted epitope) |
| Purity (RP-HPLC) | ≥95.0% |
| Solubility | Soluble in DMSO, PBS, or sterile water (may require brief sonication) |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | HLA-A*0201-restricted cytotoxic T lymphocyte (CTL) epitope derived from Hepatitis B virus polymerase; used in immunotherapy research, T-cell activation studies, and vaccine development for HBV infection. |
| Storage Conditions | Store at –20°C, protected from light and moisture. For long-term storage, recommend –80°C. |
| Stock Location | Stock in USA |
| MOQ | 10mg |
1.MECHANISM OF ACTION
HBV polymerase (455-463) acts as a HLA-A*0201-restricted cytotoxic T lymphocyte (CTL) epitope derived from the viral polymerase. When processed and presented by antigen-presenting cells, it activates virus-specific CTLs, which can recognize and eliminate HBV-infected hepatocytes, thereby contributing to a targeted antiviral immune response.
2.PRODUCT INDICATIONS
This peptide is used in HBV immunotherapy research, T-cell activation studies, epitope mapping, and the development of therapeutic vaccines. It is also applied in immunological assays and preclinical studies evaluating adaptive immune responses against HBV infection.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical studies indicate that peptides targeting HBV polymerase can elicit strong, virus-specific T-cell responses in model systems. While this epitope itself is not a direct therapeutic, its immunogenic properties support its use as a tool for developing and evaluating HBV-specific immunotherapies and vaccine candidates.
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Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
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